Effects of ovarian cycle on hemodynamic responses during dynamic exercise in sedentary women

Hyun Min Choi, Charles L Stebbins, Hosung Nho, Mi Song Kim, Myoung Jei Chang, Jong Kyung Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This study tested the hypothesis that effects of the menstrual cycle on resting blood pressure carry over to dynamic exercise. Eleven healthy females were studied during the early (EP; low estrogen, low progesterone) and late follicular (LP; high estrogen, low progesterone) menstrual phases. Stroke volume (SV), heart rate (HR), cardiac output (CO), systolic blood pressure (SBP), diastolic blood pressure (DBP), and total vascular conductance (TVC) were assessed at rest and in response to mild and moderate cycling exercise during EP and LP. During EP, compared to LP, baseline SBP (111±1 vs. 103±2 mmHg), DBP (71±2 vs. 65±2 mmHg) and mean arterial pressure (MAP) (84±2 vs. 78±1 mmHg) were higher and TVC (47.0±1.5 vs. 54.9±4.2 ml/min/mmHg) was lower (p< 0.05). During exercise, absolute values of SBP (Mild: 142±4 vs. 127±5 mmHg; Moderate: 157±4 vs. 144±5 mmHg) and MAP (Mild: 100±3 vs. 91±3 mmHg; Moderate: 110±3 vs. 101±3 mmHg) were also higher, while TVC was lower (Mild: 90.9±5.1 vs. 105.4±5.2 ml/min/mmHg; Moderate: 105.4±5.3 vs. 123.9±8.1 ml/ min/mmHg) during EP (p<0.05). However, exercise-induced increases in SBP, MAP and TVC at both work intensities were similar between the two menstrual phases, even though norepinephrine concentrations were higher during LP. Results indicate that blood pressure during dynamic exercise fluctuates during the menstrual cycle. It is higher during EP than LP and appears to be due to additive effects of simultaneous increases in baseline blood pressure and reductions in baseline TVC.

Original languageEnglish (US)
Pages (from-to)499-503
Number of pages5
JournalKorean Journal of Physiology and Pharmacology
Volume17
Issue number6
DOIs
StatePublished - Dec 2013

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Menstrual Cycle
Hemodynamics
Exercise
Blood Pressure
Blood Vessels
Arterial Pressure
Progesterone
Estrogens
Cardiac Output
Stroke Volume
Norepinephrine

Keywords

  • Blood pressure
  • Dynamic exercise
  • Estrogen
  • Menstrual cycle
  • Vascular conductance

ASJC Scopus subject areas

  • Pharmacology
  • Physiology

Cite this

Effects of ovarian cycle on hemodynamic responses during dynamic exercise in sedentary women. / Choi, Hyun Min; Stebbins, Charles L; Nho, Hosung; Kim, Mi Song; Chang, Myoung Jei; Kim, Jong Kyung.

In: Korean Journal of Physiology and Pharmacology, Vol. 17, No. 6, 12.2013, p. 499-503.

Research output: Contribution to journalArticle

Choi, Hyun Min ; Stebbins, Charles L ; Nho, Hosung ; Kim, Mi Song ; Chang, Myoung Jei ; Kim, Jong Kyung. / Effects of ovarian cycle on hemodynamic responses during dynamic exercise in sedentary women. In: Korean Journal of Physiology and Pharmacology. 2013 ; Vol. 17, No. 6. pp. 499-503.
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