Adrenal secretion and binding studies were performed using ring E analogues of methyllycaconitine to assess structural determinants affecting activity on bovine adrenal α3β4* nicotinic receptors. The most potent analogues are as potent as many inhibitors of adrenal secretion. Our data support the potential use of methyllycaconitine analogues to generate nicotinic receptor subtype-specific compounds.
|Original language||English (US)|
|Number of pages||3|
|Journal||Annals of the New York Academy of Sciences|
|State||Published - Jun 5 2002|
- Adrenal α3β4 nicotinic acetylcholine receptors
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)