Effects of environmental tobacco smoke in vitro on rhesus monkey sperm function

Pei Hsuan Hung, Julie Baumber, Stuart A Meyers, Catherine A. VandeVoort

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The objective of this study was to use a non-human primate model to examine the effect of ETS on sperm function. Sperm samples were collected from adult rhesus monkeys (Macaca mulatta) and treated with different levels of ETS exposed medium. ETS treatment decreased the percentage of motile sperm and motion parameters. Sperm treated with ETS exposed medium showed a limited response to the activators and exhibited decreased binding to the zonae pellucida after activation. The mitochondrial integrity of the ETS-treated sperm was disrupted; however, there was no decrease in viability compared to control groups. Sperm acrosomal status was similar in the control and treatment groups. The results imply that the exposure of primate sperm to ETS could impair sperm transport in vivo.

Original languageEnglish (US)
Pages (from-to)499-506
Number of pages8
JournalReproductive Toxicology
Volume23
Issue number4
DOIs
StatePublished - Jun 2007

Fingerprint

Tobacco
Macaca mulatta
Smoke
Spermatozoa
Chemical activation
Primates
Sperm Transport
Zona Pellucida
Control Groups
In Vitro Techniques

Keywords

  • Acrosome reaction
  • Environmental tobacco smoke
  • In vitro
  • Non-human primate
  • Reproduction
  • Rhesus macaque
  • Sperm
  • Sperm motility

ASJC Scopus subject areas

  • Toxicology

Cite this

Effects of environmental tobacco smoke in vitro on rhesus monkey sperm function. / Hung, Pei Hsuan; Baumber, Julie; Meyers, Stuart A; VandeVoort, Catherine A.

In: Reproductive Toxicology, Vol. 23, No. 4, 06.2007, p. 499-506.

Research output: Contribution to journalArticle

Hung, Pei Hsuan ; Baumber, Julie ; Meyers, Stuart A ; VandeVoort, Catherine A. / Effects of environmental tobacco smoke in vitro on rhesus monkey sperm function. In: Reproductive Toxicology. 2007 ; Vol. 23, No. 4. pp. 499-506.
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