Effects of Different Vitamin C-Enriched Collagen Derivatives on Collagen Synthesis

Dana M. Lis, Keith Baar

Research output: Contribution to journalArticle

Abstract

Nutritional strategies to improve connective tissue collagen synthesis have garnered significant interest, although the scientific validity of these interventions lags behind their hype. This study was designed to determine the effects of three forms of collagen on N-terminal peptide of procollagen and serum amino acid levels. A total of 10 recreationally active males completed a randomized double-blinded crossover design study consuming either placebo or 15 g of vitamin C-enriched gelatin or hydrolyzed collagen (HC), or gummy containing equal parts of gelatin and HC. Supplements were consumed 1 hr before 6 min of jump rope. Blood samples were collected immediately prior to supplement consumption and 4 hr after jump rope. A subset of blood samples (n = 4) was collected for amino acid analysis 1 hr after ingestion. Consumption of an equivalent dose of each supplement increased amino acids in the circulation similarly across all interventions. N-terminal peptide of procollagen levels tended to increase ∼20% from baseline in the gelatin and HC interventions but not the placebo or gummy. These results suggest that vitamin C-enriched gelatin and HC supplementation may improve collagen synthesis when taken 1 hr prior to exercise. However, large variability was observed, which precluded significance for any treatment.

Original languageEnglish (US)
Pages (from-to)526-531
Number of pages6
JournalInternational journal of sport nutrition and exercise metabolism
Volume29
Issue number5
DOIs
StatePublished - Sep 1 2019

Fingerprint

Ascorbic Acid
Collagen
Gelatin
Procollagen
Amino Acids
Cross-Over Studies
Placebos
Peptides
Connective Tissue
Eating
Serum

Keywords

  • exercise
  • gelatin
  • injury
  • musculoskeletal
  • N-terminal peptide of procollagen

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Nutrition and Dietetics

Cite this

Effects of Different Vitamin C-Enriched Collagen Derivatives on Collagen Synthesis. / Lis, Dana M.; Baar, Keith.

In: International journal of sport nutrition and exercise metabolism, Vol. 29, No. 5, 01.09.2019, p. 526-531.

Research output: Contribution to journalArticle

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