Abstract
1. Because the cat lacks the ability to synthesize a significant amount of arachidonate from linoleate in the liver, arachidonate is a dietary essential. We studied the effects of essential fatty acid deficiency on the aggregation of cat platelets. 2. Cat platelets aggregated in response to ADP, collagen, arachidonate and epinephrine. 3. Aggregation was impaired in platelets from cats fed arachidonate-deficient diets. 4. Including a source of linoleate in the arachidonate-deficient diet did not improve aggregation. 5. Arachidonate is required in the diet of the cat for normal platelet aggregation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 123-126 |
| Number of pages | 4 |
| Journal | Comparative Biochemistry and Physiology. Part C, Comparative |
| Volume | 78 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1984 |
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ASJC Scopus subject areas
- Immunology
- Pharmacology
Cite this
Effects of dietary arachidonate deficiency on the aggregation of cat platelets. / MacDonald, Marnie L.; Rogers, Quinton; Morris, James.
In: Comparative Biochemistry and Physiology. Part C, Comparative, Vol. 78, No. 1, 01.01.1984, p. 123-126.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of dietary arachidonate deficiency on the aggregation of cat platelets
AU - MacDonald, Marnie L.
AU - Rogers, Quinton
AU - Morris, James
PY - 1984/1/1
Y1 - 1984/1/1
N2 - 1. Because the cat lacks the ability to synthesize a significant amount of arachidonate from linoleate in the liver, arachidonate is a dietary essential. We studied the effects of essential fatty acid deficiency on the aggregation of cat platelets. 2. Cat platelets aggregated in response to ADP, collagen, arachidonate and epinephrine. 3. Aggregation was impaired in platelets from cats fed arachidonate-deficient diets. 4. Including a source of linoleate in the arachidonate-deficient diet did not improve aggregation. 5. Arachidonate is required in the diet of the cat for normal platelet aggregation.
AB - 1. Because the cat lacks the ability to synthesize a significant amount of arachidonate from linoleate in the liver, arachidonate is a dietary essential. We studied the effects of essential fatty acid deficiency on the aggregation of cat platelets. 2. Cat platelets aggregated in response to ADP, collagen, arachidonate and epinephrine. 3. Aggregation was impaired in platelets from cats fed arachidonate-deficient diets. 4. Including a source of linoleate in the arachidonate-deficient diet did not improve aggregation. 5. Arachidonate is required in the diet of the cat for normal platelet aggregation.
UR - http://www.scopus.com/inward/record.url?scp=0021253271&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021253271&partnerID=8YFLogxK
U2 - 10.1016/0742-8413(84)90057-4
DO - 10.1016/0742-8413(84)90057-4
M3 - Article
C2 - 6146457
AN - SCOPUS:0021253271
VL - 78
SP - 123
EP - 126
JO - Comparative biochemistry and physiology. C: Comparative pharmacology
JF - Comparative biochemistry and physiology. C: Comparative pharmacology
SN - 0742-8413
IS - 1
ER -