Effects of dietary arachidonate deficiency on the aggregation of cat platelets

Marnie L. MacDonald, Quinton Rogers, James Morris

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

1. Because the cat lacks the ability to synthesize a significant amount of arachidonate from linoleate in the liver, arachidonate is a dietary essential. We studied the effects of essential fatty acid deficiency on the aggregation of cat platelets. 2. Cat platelets aggregated in response to ADP, collagen, arachidonate and epinephrine. 3. Aggregation was impaired in platelets from cats fed arachidonate-deficient diets. 4. Including a source of linoleate in the arachidonate-deficient diet did not improve aggregation. 5. Arachidonate is required in the diet of the cat for normal platelet aggregation.

Original languageEnglish (US)
Pages (from-to)123-126
Number of pages4
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume78
Issue number1
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

Fingerprint Dive into the research topics of 'Effects of dietary arachidonate deficiency on the aggregation of cat platelets'. Together they form a unique fingerprint.

  • Cite this