Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise

Jason W. Daniels, Paul A. Molé, James D. Shaffrath, Charles L Stebbins

Research output: Contribution to journalArticle

85 Citations (Scopus)

Abstract

This study examined the acute effects of caffeine on the cardiovascular system during dynamic leg exercise. Ten trained, caffeine-naive Cyclists (7 women and 3 men) were studied at rest and during bicycle ergometry before and after the ingestion of 6 mg/kg caffeine or 6 mg/kg fructose (placebo) with 250 ml of water. After consumption of caffeine or placebo, subjects either rested for 100 min (rest protocol) or rested for 45 min followed by 55 min of cycle ergometry at 65% of maximal oxygen consumption (exercise protocol). Measurement of mean arterial pressure (MAP), forearm blood flow (FBF), heart rate, skin temperature, and rectal temperature and calculation of forearm vascular conductance (FVC) were made at baseline and at 20-min intervals. Plasma ANG II was measured at baseline and at 60 min postingestion in the two exercise protocols. Before exercise, caffeine increased both systolic blood pressure (17%) and MAP (11%) without affecting FBF or FVC. During dynamic exercise, caffeine attenuated the increase in FBF (53%) and FVC (50%) and accentuated exercise-induced increases in ANG II (44%). Systolic blood pressure and MAP were also higher during exercise plus caffeine; however, these increases were secondary to the effects of caffeine on resting blood pressure. No significant differences were observed in heart rate, skin temperature, or rectal temperature. These findings indicate that caffeine can alter the cardiovascular response to dynamic exercise in a manner that may modify regional blood flow and conductance.

Original languageEnglish (US)
Pages (from-to)154-159
Number of pages6
JournalJournal of Applied Physiology
Volume85
Issue number1
StatePublished - 1998

Fingerprint

Caffeine
Forearm
Leg
Heart Rate
Exercise
Blood Pressure
Blood Vessels
Ergometry
Arterial Pressure
Skin Temperature
Placebos
Temperature
Regional Blood Flow
Cardiovascular System
Fructose
Oxygen Consumption
Eating
Water

Keywords

  • Adenosine receptors
  • Angiotensin II
  • Forearm vascular conductance

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Daniels, J. W., Molé, P. A., Shaffrath, J. D., & Stebbins, C. L. (1998). Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise. Journal of Applied Physiology, 85(1), 154-159.

Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise. / Daniels, Jason W.; Molé, Paul A.; Shaffrath, James D.; Stebbins, Charles L.

In: Journal of Applied Physiology, Vol. 85, No. 1, 1998, p. 154-159.

Research output: Contribution to journalArticle

Daniels, JW, Molé, PA, Shaffrath, JD & Stebbins, CL 1998, 'Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise', Journal of Applied Physiology, vol. 85, no. 1, pp. 154-159.
Daniels, Jason W. ; Molé, Paul A. ; Shaffrath, James D. ; Stebbins, Charles L. / Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise. In: Journal of Applied Physiology. 1998 ; Vol. 85, No. 1. pp. 154-159.
@article{f575c7a3fc54407da58417d40f2af3f8,
title = "Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise",
abstract = "This study examined the acute effects of caffeine on the cardiovascular system during dynamic leg exercise. Ten trained, caffeine-naive Cyclists (7 women and 3 men) were studied at rest and during bicycle ergometry before and after the ingestion of 6 mg/kg caffeine or 6 mg/kg fructose (placebo) with 250 ml of water. After consumption of caffeine or placebo, subjects either rested for 100 min (rest protocol) or rested for 45 min followed by 55 min of cycle ergometry at 65{\%} of maximal oxygen consumption (exercise protocol). Measurement of mean arterial pressure (MAP), forearm blood flow (FBF), heart rate, skin temperature, and rectal temperature and calculation of forearm vascular conductance (FVC) were made at baseline and at 20-min intervals. Plasma ANG II was measured at baseline and at 60 min postingestion in the two exercise protocols. Before exercise, caffeine increased both systolic blood pressure (17{\%}) and MAP (11{\%}) without affecting FBF or FVC. During dynamic exercise, caffeine attenuated the increase in FBF (53{\%}) and FVC (50{\%}) and accentuated exercise-induced increases in ANG II (44{\%}). Systolic blood pressure and MAP were also higher during exercise plus caffeine; however, these increases were secondary to the effects of caffeine on resting blood pressure. No significant differences were observed in heart rate, skin temperature, or rectal temperature. These findings indicate that caffeine can alter the cardiovascular response to dynamic exercise in a manner that may modify regional blood flow and conductance.",
keywords = "Adenosine receptors, Angiotensin II, Forearm vascular conductance",
author = "Daniels, {Jason W.} and Mol{\'e}, {Paul A.} and Shaffrath, {James D.} and Stebbins, {Charles L}",
year = "1998",
language = "English (US)",
volume = "85",
pages = "154--159",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "1",

}

TY - JOUR

T1 - Effects of caffeine on blood pressure, heart rate, and forearm blood flow during dynamic leg exercise

AU - Daniels, Jason W.

AU - Molé, Paul A.

AU - Shaffrath, James D.

AU - Stebbins, Charles L

PY - 1998

Y1 - 1998

N2 - This study examined the acute effects of caffeine on the cardiovascular system during dynamic leg exercise. Ten trained, caffeine-naive Cyclists (7 women and 3 men) were studied at rest and during bicycle ergometry before and after the ingestion of 6 mg/kg caffeine or 6 mg/kg fructose (placebo) with 250 ml of water. After consumption of caffeine or placebo, subjects either rested for 100 min (rest protocol) or rested for 45 min followed by 55 min of cycle ergometry at 65% of maximal oxygen consumption (exercise protocol). Measurement of mean arterial pressure (MAP), forearm blood flow (FBF), heart rate, skin temperature, and rectal temperature and calculation of forearm vascular conductance (FVC) were made at baseline and at 20-min intervals. Plasma ANG II was measured at baseline and at 60 min postingestion in the two exercise protocols. Before exercise, caffeine increased both systolic blood pressure (17%) and MAP (11%) without affecting FBF or FVC. During dynamic exercise, caffeine attenuated the increase in FBF (53%) and FVC (50%) and accentuated exercise-induced increases in ANG II (44%). Systolic blood pressure and MAP were also higher during exercise plus caffeine; however, these increases were secondary to the effects of caffeine on resting blood pressure. No significant differences were observed in heart rate, skin temperature, or rectal temperature. These findings indicate that caffeine can alter the cardiovascular response to dynamic exercise in a manner that may modify regional blood flow and conductance.

AB - This study examined the acute effects of caffeine on the cardiovascular system during dynamic leg exercise. Ten trained, caffeine-naive Cyclists (7 women and 3 men) were studied at rest and during bicycle ergometry before and after the ingestion of 6 mg/kg caffeine or 6 mg/kg fructose (placebo) with 250 ml of water. After consumption of caffeine or placebo, subjects either rested for 100 min (rest protocol) or rested for 45 min followed by 55 min of cycle ergometry at 65% of maximal oxygen consumption (exercise protocol). Measurement of mean arterial pressure (MAP), forearm blood flow (FBF), heart rate, skin temperature, and rectal temperature and calculation of forearm vascular conductance (FVC) were made at baseline and at 20-min intervals. Plasma ANG II was measured at baseline and at 60 min postingestion in the two exercise protocols. Before exercise, caffeine increased both systolic blood pressure (17%) and MAP (11%) without affecting FBF or FVC. During dynamic exercise, caffeine attenuated the increase in FBF (53%) and FVC (50%) and accentuated exercise-induced increases in ANG II (44%). Systolic blood pressure and MAP were also higher during exercise plus caffeine; however, these increases were secondary to the effects of caffeine on resting blood pressure. No significant differences were observed in heart rate, skin temperature, or rectal temperature. These findings indicate that caffeine can alter the cardiovascular response to dynamic exercise in a manner that may modify regional blood flow and conductance.

KW - Adenosine receptors

KW - Angiotensin II

KW - Forearm vascular conductance

UR - http://www.scopus.com/inward/record.url?scp=0031855496&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031855496&partnerID=8YFLogxK

M3 - Article

C2 - 9655769

AN - SCOPUS:0031855496

VL - 85

SP - 154

EP - 159

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 1

ER -