Effects of a restrictive blood transfusion policy on outcomes in children with burn injury

Tina L Palmieri, Terry Lee, Michael S. O'Mara, David G Greenhalgh

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

A restrictive blood transfusion policy decreases blood utilization and improves outcomes in critically ill adults, but the impact of a restrictive blood transfusion policy in critically ill children is unclear. The study purpose was to compare the effects of a restrictive with a traditional blood transfusion policy in children with major burn injury. A retrospective review of all blood transfusions administered in a pediatric burn center during a 5-year period was conducted. Children in the traditional group (January 1, 2000, to June 30, 2002), were transfused at a hemoglobin level of less than 10 g/dl. Children in the restrictive group (January 1, 2003, to June 30, 2005, 6 months after the adoption of a restrictive protocol) were transfused at a hemoglobin level of less than 7 g/dl. Patient groups were compared for demographics, ventilator requirements, blood transfusion number, transfusion costs, and outcomes. Of the 1140 patients studied, 266 (24%) received a total of 2577 units of blood. There was no difference in age, TBSA burn, sex, inhalation injury, or mortality between groups. Patients in the traditional group received more blood than the restrictive group (12.3 ± 1.8 vs 7.2 ± 1.2 units/patient, P < .001). The mean cost of blood per patient was $2781 for the traditional group and $1489 for the restrictive group. A restrictive transfusion policy in children with burn injury decreases the amount of blood transfused, does not adversely impact patient outcome, and results in significant cost savings to the institution.

Original languageEnglish (US)
Pages (from-to)65-70
Number of pages6
JournalJournal of Burn Care and Research
Volume28
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

ASJC Scopus subject areas

  • Emergency Medicine
  • Rehabilitation
  • Surgery

Fingerprint Dive into the research topics of 'Effects of a restrictive blood transfusion policy on outcomes in children with burn injury'. Together they form a unique fingerprint.

  • Cite this