Abstract
Previous studies have shown that the intake of freeze-dried strawberry powder (FDSP) improves select markers of cardiovascular health in adults with cardiovascular risk factors; however, whether these improvements can be observed in at-risk adolescents is unknown. A randomised, double-blind, cross-over study enrolled twenty-five overweight or obese males, aged 14-18 years, to consume 50 g of a FDSP or a control powder, daily for 1 week. Before and after each test period, measures of microvascular function, plasma nitrate/nitrite, platelet reactivity and blood lipids were collected at baseline and acutely 1 h after FDSP intake. Acute plasma nitrate/nitrite levels increased 1 h after consuming the FDSP during Study Visit 1 before daily FDSP intake (P<0·001) and during Study Visit 2 after 1 week of FDSP intake (P<0·001) compared with control powder intake. As a group, fasting nitrate/nitrite levels did not significantly change after 1 week of control or FDSP intake. However, for those individuals where fasting nitrate levels increased after short-term FDSP intake compared with controls, an increase in reactive hyperaemia index (RHI) was observed (P=0·014), whereas RHI was unchanged in those individuals who did not have a significant increase in nitrate (P=0·396). Taken together, these data support the concept that strawberries can provide vascular health benefits to heavier adolescent males.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 639-647 |
| Number of pages | 9 |
| Journal | British Journal of Nutrition |
| Volume | 116 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 28 2016 |
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Keywords
- Nitrate
- Obese adolescents
- Peripheral arterial tonometry
- Strawberry powder
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
Cite this
Effects of a dietary strawberry powder on parameters of vascular health in adolescent males. / Djurica, Dragana; Holt, Roberta R.; Ren, Jingyan; Shindel, Alan W; Hackman, Robert M.; Keen, Carl L.
In: British Journal of Nutrition, Vol. 116, No. 4, 28.08.2016, p. 639-647.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of a dietary strawberry powder on parameters of vascular health in adolescent males
AU - Djurica, Dragana
AU - Holt, Roberta R.
AU - Ren, Jingyan
AU - Shindel, Alan W
AU - Hackman, Robert M.
AU - Keen, Carl L
PY - 2016/8/28
Y1 - 2016/8/28
N2 - Previous studies have shown that the intake of freeze-dried strawberry powder (FDSP) improves select markers of cardiovascular health in adults with cardiovascular risk factors; however, whether these improvements can be observed in at-risk adolescents is unknown. A randomised, double-blind, cross-over study enrolled twenty-five overweight or obese males, aged 14-18 years, to consume 50 g of a FDSP or a control powder, daily for 1 week. Before and after each test period, measures of microvascular function, plasma nitrate/nitrite, platelet reactivity and blood lipids were collected at baseline and acutely 1 h after FDSP intake. Acute plasma nitrate/nitrite levels increased 1 h after consuming the FDSP during Study Visit 1 before daily FDSP intake (P<0·001) and during Study Visit 2 after 1 week of FDSP intake (P<0·001) compared with control powder intake. As a group, fasting nitrate/nitrite levels did not significantly change after 1 week of control or FDSP intake. However, for those individuals where fasting nitrate levels increased after short-term FDSP intake compared with controls, an increase in reactive hyperaemia index (RHI) was observed (P=0·014), whereas RHI was unchanged in those individuals who did not have a significant increase in nitrate (P=0·396). Taken together, these data support the concept that strawberries can provide vascular health benefits to heavier adolescent males.
AB - Previous studies have shown that the intake of freeze-dried strawberry powder (FDSP) improves select markers of cardiovascular health in adults with cardiovascular risk factors; however, whether these improvements can be observed in at-risk adolescents is unknown. A randomised, double-blind, cross-over study enrolled twenty-five overweight or obese males, aged 14-18 years, to consume 50 g of a FDSP or a control powder, daily for 1 week. Before and after each test period, measures of microvascular function, plasma nitrate/nitrite, platelet reactivity and blood lipids were collected at baseline and acutely 1 h after FDSP intake. Acute plasma nitrate/nitrite levels increased 1 h after consuming the FDSP during Study Visit 1 before daily FDSP intake (P<0·001) and during Study Visit 2 after 1 week of FDSP intake (P<0·001) compared with control powder intake. As a group, fasting nitrate/nitrite levels did not significantly change after 1 week of control or FDSP intake. However, for those individuals where fasting nitrate levels increased after short-term FDSP intake compared with controls, an increase in reactive hyperaemia index (RHI) was observed (P=0·014), whereas RHI was unchanged in those individuals who did not have a significant increase in nitrate (P=0·396). Taken together, these data support the concept that strawberries can provide vascular health benefits to heavier adolescent males.
KW - Nitrate
KW - Obese adolescents
KW - Peripheral arterial tonometry
KW - Strawberry powder
UR - http://www.scopus.com/inward/record.url?scp=84979997627&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84979997627&partnerID=8YFLogxK
U2 - 10.1017/S0007114516002348
DO - 10.1017/S0007114516002348
M3 - Article
C2 - 27464461
AN - SCOPUS:84979997627
VL - 116
SP - 639
EP - 647
JO - British Journal of Nutrition
JF - British Journal of Nutrition
SN - 0007-1145
IS - 4
ER -