Effects and residues of dietary hexachlorobenzene in growing swine

L. G. Hansen, Dennis W Wilson, C. S. Byerly, S. F. Sundlof, S. B. Dorn

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Crossbred weanling gilts were fed a standard ration containing 0, 1, 10, or 100 ppm purified hexachlorobenzene (HCB) for 13 wk. No mortalities, ill health, neurological disorders, or significant depressions in weight gain were observed. Postmortem examination revealed brightly fluorescent livers at all levels of HCB. The group receiving 100 ppm had a tendency for smaller spleens, larger livers with swollen hepatocytes, and decreased lymphocytes. HCB accumulated in the dissectable fat of growing swine to concentrations five- to sevenfold higher than the dietary concentration; residues in 11 other tissues examined were below the dietary concentration.

Original languageEnglish (US)
Pages (from-to)557-567
Number of pages11
JournalJournal of Toxicology and Environmental Health
Volume2
Issue number3
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Toxicology
  • Pollution

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    Hansen, L. G., Wilson, D. W., Byerly, C. S., Sundlof, S. F., & Dorn, S. B. (1977). Effects and residues of dietary hexachlorobenzene in growing swine. Journal of Toxicology and Environmental Health, 2(3), 557-567.