Effective atomic number and electron density as measured with a computed tomography scanner

computation and correlation with brain tumor histology

Richard E Latchaw, J. R. Payne, L. H A Gold

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The mathematical basis and methodology for determining the effective atomic number and electron density of a tissue are presented. Cranial computed tomography (CT) scanning is performed at two different energy levels, both with and without contrast enhancement. The histology of 15 brain tumors has been correlated with the effective atomic number and electron density of the tumor, with parameters of the linear attenuation coefficient, and with statistical values of the CT numbers. The most useful value in separating gliomas from meningiomas from metastases appears to be the percentage change of effective atomic number following contrast enhancement.

Original languageEnglish (US)
Pages (from-to)199-208
Number of pages10
JournalJournal of Computer Assisted Tomography
Volume2
Issue number2
StatePublished - 1978
Externally publishedYes

Fingerprint

X-Ray Computed Tomography Scanners
Brain Neoplasms
Histology
Tomography
Electrons
Meningioma
Glioma
Neoplasm Metastasis
Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

@article{5248ecea03c845d090953bd04aa93b7b,
title = "Effective atomic number and electron density as measured with a computed tomography scanner: computation and correlation with brain tumor histology",
abstract = "The mathematical basis and methodology for determining the effective atomic number and electron density of a tissue are presented. Cranial computed tomography (CT) scanning is performed at two different energy levels, both with and without contrast enhancement. The histology of 15 brain tumors has been correlated with the effective atomic number and electron density of the tumor, with parameters of the linear attenuation coefficient, and with statistical values of the CT numbers. The most useful value in separating gliomas from meningiomas from metastases appears to be the percentage change of effective atomic number following contrast enhancement.",
author = "Latchaw, {Richard E} and Payne, {J. R.} and Gold, {L. H A}",
year = "1978",
language = "English (US)",
volume = "2",
pages = "199--208",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Effective atomic number and electron density as measured with a computed tomography scanner

T2 - computation and correlation with brain tumor histology

AU - Latchaw, Richard E

AU - Payne, J. R.

AU - Gold, L. H A

PY - 1978

Y1 - 1978

N2 - The mathematical basis and methodology for determining the effective atomic number and electron density of a tissue are presented. Cranial computed tomography (CT) scanning is performed at two different energy levels, both with and without contrast enhancement. The histology of 15 brain tumors has been correlated with the effective atomic number and electron density of the tumor, with parameters of the linear attenuation coefficient, and with statistical values of the CT numbers. The most useful value in separating gliomas from meningiomas from metastases appears to be the percentage change of effective atomic number following contrast enhancement.

AB - The mathematical basis and methodology for determining the effective atomic number and electron density of a tissue are presented. Cranial computed tomography (CT) scanning is performed at two different energy levels, both with and without contrast enhancement. The histology of 15 brain tumors has been correlated with the effective atomic number and electron density of the tumor, with parameters of the linear attenuation coefficient, and with statistical values of the CT numbers. The most useful value in separating gliomas from meningiomas from metastases appears to be the percentage change of effective atomic number following contrast enhancement.

UR - http://www.scopus.com/inward/record.url?scp=0018170829&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018170829&partnerID=8YFLogxK

M3 - Article

VL - 2

SP - 199

EP - 208

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

IS - 2

ER -