Effect of topical atropine on intraocular pressure and pupil diameter in the normal horse eye

Albert J. Mughannam, Nedim C. Buyukmihci, Philip H Kass

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

The objective was to determine whether topically administered 1% atropine would alter intraocular pressure. The animals studied were four healthy adult horses. Intraocular pressure and pupil diameter were measured prior to and during a 2-day period of treatment with 1% atropine sulfate. No significant changes in intraocular pressure occurred as a result of the treatment with atropine. Pupil diameter increased significantly after atropine was applied. Available information on the outflow of aqueous humor from the horse eye suggests that atropine might reduce intraocular pressure in the horse by increasing uveoscleral outflow. This could prove beneficial in the treatment of equine glaucoma. We could not confirm a significant pressure-lowering effect of atropine. It is possible, however, that a longer treatment period may be required or that atropine may have a more profound effect on glaucomatous globes.

Original languageEnglish (US)
Pages (from-to)213-215
Number of pages3
JournalVeterinary Ophthalmology
Volume2
Issue number4
StatePublished - 1999

Keywords

  • Atropine
  • Glaucoma
  • Horse
  • Treatment

ASJC Scopus subject areas

  • Ophthalmology
  • veterinary(all)

Fingerprint Dive into the research topics of 'Effect of topical atropine on intraocular pressure and pupil diameter in the normal horse eye'. Together they form a unique fingerprint.

Cite this