Effect of sleep on the electrographic manifestations of epilepsy

A. J. Gabor, Masud Seyal

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Alterations in the level of arousal have profound predictable effects on the electrographic manifestations of epileptogenic abnormalities. The changes produced by sleep are dramatic in patients with generalized epilepsy as compared to patients with partial epilepsy. The epileptiform complexes associated with the generalized epilepsies show changes in spatial distribution, voltage, temporal sequencing, and waveform morphology. The changes are qualitatively similar in the different types of generalized seizure disorders but vary in the degree to which they are expressed in proportion to the 'severity' of the seizure disorder. The presence of a generalized epileptogenic abnormality may result in alteration of K-complex waveform morphology. Multifocal spikes occurring in conjunction with bilateral synchronous discharges are frequently represented by a spatial field distribution consistent with a 'horizontal dipole', during sleep especially in children.

Original languageEnglish (US)
Pages (from-to)23-38
Number of pages16
JournalJournal of Clinical Neurophysiology
Volume3
Issue number1
StatePublished - 1986

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Generalized Epilepsy
Epilepsy
Sleep
Partial Epilepsy
Arousal

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Effect of sleep on the electrographic manifestations of epilepsy. / Gabor, A. J.; Seyal, Masud.

In: Journal of Clinical Neurophysiology, Vol. 3, No. 1, 1986, p. 23-38.

Research output: Contribution to journalArticle

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