Effect of pulmonary hypertension on lung compliance in newborn lambs.

A. J. Caeton, B. W. Goetzman, S. H. Bennett, Jay M Milstein

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We studied the effects of increased pulmonary arterial pressure and vascular resistance on lung compliance in 12 anesthetized newborn lambs. Lung compliance was unaffected by large changes in pulmonary artery pressure and pulmonary vascular resistance (80% increase) that were induced by either hypoxia or acidosis. We conclude that contraction of the pulmonary vascular smooth muscle in normal newborn lambs does not affect the stiffness of the lung in the parenchymal regions undergoing volume change during ventilation.

Original languageEnglish (US)
Pages (from-to)324-327
Number of pages4
JournalPediatric Pulmonology
Volume3
Issue number5
StatePublished - Sep 1987

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Lung Compliance
Pulmonary Hypertension
Vascular Resistance
Lung
Acidosis
Vascular Smooth Muscle
Pulmonary Artery
Ventilation
Arterial Pressure
Pressure

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

Caeton, A. J., Goetzman, B. W., Bennett, S. H., & Milstein, J. M. (1987). Effect of pulmonary hypertension on lung compliance in newborn lambs. Pediatric Pulmonology, 3(5), 324-327.

Effect of pulmonary hypertension on lung compliance in newborn lambs. / Caeton, A. J.; Goetzman, B. W.; Bennett, S. H.; Milstein, Jay M.

In: Pediatric Pulmonology, Vol. 3, No. 5, 09.1987, p. 324-327.

Research output: Contribution to journalArticle

Caeton, AJ, Goetzman, BW, Bennett, SH & Milstein, JM 1987, 'Effect of pulmonary hypertension on lung compliance in newborn lambs.', Pediatric Pulmonology, vol. 3, no. 5, pp. 324-327.
Caeton, A. J. ; Goetzman, B. W. ; Bennett, S. H. ; Milstein, Jay M. / Effect of pulmonary hypertension on lung compliance in newborn lambs. In: Pediatric Pulmonology. 1987 ; Vol. 3, No. 5. pp. 324-327.
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