Abstract
Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 293-298 |
| Number of pages | 6 |
| Journal | Journal of Pediatrics |
| Volume | 151 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2007 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index. / Abrams, Steven A.; Griffin, Ian J.; Hawthorne, Keli M.; Ellis, Kenneth J.
In: Journal of Pediatrics, Vol. 151, No. 3, 09.2007, p. 293-298.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index
AU - Abrams, Steven A.
AU - Griffin, Ian J.
AU - Hawthorne, Keli M.
AU - Ellis, Kenneth J.
PY - 2007/9
Y1 - 2007/9
N2 - Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.
AB - Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.
UR - http://www.scopus.com/inward/record.url?scp=34548140139&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548140139&partnerID=8YFLogxK
U2 - 10.1016/j.jpeds.2007.03.043
DO - 10.1016/j.jpeds.2007.03.043
M3 - Article
C2 - 17719942
AN - SCOPUS:34548140139
VL - 151
SP - 293
EP - 298
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 3
ER -