Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index

Steven A. Abrams, Ian J. Griffin, Keli M. Hawthorne, Kenneth J. Ellis

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.

Original languageEnglish (US)
Pages (from-to)293-298
Number of pages6
JournalJournal of Pediatrics
Volume151
Issue number3
DOIs
StatePublished - Sep 2007
Externally publishedYes

Fingerprint

Prebiotics
Body Mass Index
Calcium
Body Composition
Control Groups
Anthropometry
Photon Absorptiometry
Puberty
Adipose Tissue
Fats
Growth

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Abrams, S. A., Griffin, I. J., Hawthorne, K. M., & Ellis, K. J. (2007). Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index. Journal of Pediatrics, 151(3), 293-298. https://doi.org/10.1016/j.jpeds.2007.03.043

Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index. / Abrams, Steven A.; Griffin, Ian J.; Hawthorne, Keli M.; Ellis, Kenneth J.

In: Journal of Pediatrics, Vol. 151, No. 3, 09.2007, p. 293-298.

Research output: Contribution to journalArticle

Abrams, SA, Griffin, IJ, Hawthorne, KM & Ellis, KJ 2007, 'Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index', Journal of Pediatrics, vol. 151, no. 3, pp. 293-298. https://doi.org/10.1016/j.jpeds.2007.03.043
Abrams, Steven A. ; Griffin, Ian J. ; Hawthorne, Keli M. ; Ellis, Kenneth J. / Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index. In: Journal of Pediatrics. 2007 ; Vol. 151, No. 3. pp. 293-298.
@article{9a0c6f09899c4878831a6bb607bcff97,
title = "Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index",
abstract = "Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.",
author = "Abrams, {Steven A.} and Griffin, {Ian J.} and Hawthorne, {Keli M.} and Ellis, {Kenneth J.}",
year = "2007",
month = "9",
doi = "10.1016/j.jpeds.2007.03.043",
language = "English (US)",
volume = "151",
pages = "293--298",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "3",

}

TY - JOUR

T1 - Effect of Prebiotic Supplementation and Calcium Intake on Body Mass Index

AU - Abrams, Steven A.

AU - Griffin, Ian J.

AU - Hawthorne, Keli M.

AU - Ellis, Kenneth J.

PY - 2007/9

Y1 - 2007/9

N2 - Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.

AB - Objective: To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth. Study design: We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year. Results: Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 ± 0.16 kg/m2, P = .016), BMI Z-score (difference 0.13 ± 0.06, P = .048) and total fat mass (difference 0.84 ± 0.36 kg, P = .022). The prebiotic group maintained their baseline BMI Z-score (0.03 ± 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 ± 0.03, P < .001). In considering subjects whose usual calcium intake was ≥700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m2 less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped. Conclusion: Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.

UR - http://www.scopus.com/inward/record.url?scp=34548140139&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548140139&partnerID=8YFLogxK

U2 - 10.1016/j.jpeds.2007.03.043

DO - 10.1016/j.jpeds.2007.03.043

M3 - Article

C2 - 17719942

AN - SCOPUS:34548140139

VL - 151

SP - 293

EP - 298

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 3

ER -