Effect of object size on scatter fraction estimation methods for PET-A computer simulation study

Andrea Ferrero, Jonathan K. Poon, Abhijit Chaudhari, Lawrence R. MacDonald, Ramsey D Badawi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Scatter fraction (SF) for PET scanners is typically estimated by making a single measurement using a solid cylindrical phantom with a line source radially offset from the center. The radial displacement of the line source is expected to give a value for scatter fraction that is representative of a typical PET scan for a scanner. A range of phantom sizes suitable for small animal and whole-body PET scanners is investigated. For whole-body imaging, we simulate phantom diameters ranging from 15 to 42 cm, whereas for small animal scanners, we simulate phantom diameters ranging from 2.5 to 15 cm. We find that the line source displacements suggested by the NEMA NU 4-2008 for three phantoms results in a scatter fraction very similar to the one that would arise from uniformly activated phantoms of similar size. On the other hand, the 20 cm phantom used for count rate performance assessment for wholebody scanners is shown to overestimate by about 25% the SF of the corresponding uniform phantom, a result that agrees well with that reported by the NEMA committee for the NU 2-2001 standard protocol. Combining the results obtained with small animal and whole-body scanners, we show that the optimal displacement of the line source for estimating the scatter fraction of an equivalent uniformly filled phantom is well approximated by a linear function of the phantom radius and is only weakly dependent on scanner size or detector material. The optimum radial displacement position appears to be at approximately four-fifths of the phantom radius from the center.

Original languageEnglish (US)
Article number5634154
Pages (from-to)82-86
Number of pages5
JournalIEEE Transactions on Nuclear Science
Volume58
Issue number1 PART 1
DOIs
StatePublished - Feb 2011

Fingerprint

scanners
Animals
computerized simulation
Computer simulation
animals
Detectors
Imaging techniques
radii
estimating
detectors

Keywords

  • PET
  • scatter fraction (SF)

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering
  • Nuclear and High Energy Physics

Cite this

Effect of object size on scatter fraction estimation methods for PET-A computer simulation study. / Ferrero, Andrea; Poon, Jonathan K.; Chaudhari, Abhijit; MacDonald, Lawrence R.; Badawi, Ramsey D.

In: IEEE Transactions on Nuclear Science, Vol. 58, No. 1 PART 1, 5634154, 02.2011, p. 82-86.

Research output: Contribution to journalArticle

@article{51f9ea400ef54028a8c875b5d6de317c,
title = "Effect of object size on scatter fraction estimation methods for PET-A computer simulation study",
abstract = "Scatter fraction (SF) for PET scanners is typically estimated by making a single measurement using a solid cylindrical phantom with a line source radially offset from the center. The radial displacement of the line source is expected to give a value for scatter fraction that is representative of a typical PET scan for a scanner. A range of phantom sizes suitable for small animal and whole-body PET scanners is investigated. For whole-body imaging, we simulate phantom diameters ranging from 15 to 42 cm, whereas for small animal scanners, we simulate phantom diameters ranging from 2.5 to 15 cm. We find that the line source displacements suggested by the NEMA NU 4-2008 for three phantoms results in a scatter fraction very similar to the one that would arise from uniformly activated phantoms of similar size. On the other hand, the 20 cm phantom used for count rate performance assessment for wholebody scanners is shown to overestimate by about 25{\%} the SF of the corresponding uniform phantom, a result that agrees well with that reported by the NEMA committee for the NU 2-2001 standard protocol. Combining the results obtained with small animal and whole-body scanners, we show that the optimal displacement of the line source for estimating the scatter fraction of an equivalent uniformly filled phantom is well approximated by a linear function of the phantom radius and is only weakly dependent on scanner size or detector material. The optimum radial displacement position appears to be at approximately four-fifths of the phantom radius from the center.",
keywords = "PET, scatter fraction (SF)",
author = "Andrea Ferrero and Poon, {Jonathan K.} and Abhijit Chaudhari and MacDonald, {Lawrence R.} and Badawi, {Ramsey D}",
year = "2011",
month = "2",
doi = "10.1109/TNS.2010.2080685",
language = "English (US)",
volume = "58",
pages = "82--86",
journal = "IEEE Transactions on Nuclear Science",
issn = "0018-9499",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "1 PART 1",

}

TY - JOUR

T1 - Effect of object size on scatter fraction estimation methods for PET-A computer simulation study

AU - Ferrero, Andrea

AU - Poon, Jonathan K.

AU - Chaudhari, Abhijit

AU - MacDonald, Lawrence R.

AU - Badawi, Ramsey D

PY - 2011/2

Y1 - 2011/2

N2 - Scatter fraction (SF) for PET scanners is typically estimated by making a single measurement using a solid cylindrical phantom with a line source radially offset from the center. The radial displacement of the line source is expected to give a value for scatter fraction that is representative of a typical PET scan for a scanner. A range of phantom sizes suitable for small animal and whole-body PET scanners is investigated. For whole-body imaging, we simulate phantom diameters ranging from 15 to 42 cm, whereas for small animal scanners, we simulate phantom diameters ranging from 2.5 to 15 cm. We find that the line source displacements suggested by the NEMA NU 4-2008 for three phantoms results in a scatter fraction very similar to the one that would arise from uniformly activated phantoms of similar size. On the other hand, the 20 cm phantom used for count rate performance assessment for wholebody scanners is shown to overestimate by about 25% the SF of the corresponding uniform phantom, a result that agrees well with that reported by the NEMA committee for the NU 2-2001 standard protocol. Combining the results obtained with small animal and whole-body scanners, we show that the optimal displacement of the line source for estimating the scatter fraction of an equivalent uniformly filled phantom is well approximated by a linear function of the phantom radius and is only weakly dependent on scanner size or detector material. The optimum radial displacement position appears to be at approximately four-fifths of the phantom radius from the center.

AB - Scatter fraction (SF) for PET scanners is typically estimated by making a single measurement using a solid cylindrical phantom with a line source radially offset from the center. The radial displacement of the line source is expected to give a value for scatter fraction that is representative of a typical PET scan for a scanner. A range of phantom sizes suitable for small animal and whole-body PET scanners is investigated. For whole-body imaging, we simulate phantom diameters ranging from 15 to 42 cm, whereas for small animal scanners, we simulate phantom diameters ranging from 2.5 to 15 cm. We find that the line source displacements suggested by the NEMA NU 4-2008 for three phantoms results in a scatter fraction very similar to the one that would arise from uniformly activated phantoms of similar size. On the other hand, the 20 cm phantom used for count rate performance assessment for wholebody scanners is shown to overestimate by about 25% the SF of the corresponding uniform phantom, a result that agrees well with that reported by the NEMA committee for the NU 2-2001 standard protocol. Combining the results obtained with small animal and whole-body scanners, we show that the optimal displacement of the line source for estimating the scatter fraction of an equivalent uniformly filled phantom is well approximated by a linear function of the phantom radius and is only weakly dependent on scanner size or detector material. The optimum radial displacement position appears to be at approximately four-fifths of the phantom radius from the center.

KW - PET

KW - scatter fraction (SF)

UR - http://www.scopus.com/inward/record.url?scp=79951683120&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79951683120&partnerID=8YFLogxK

U2 - 10.1109/TNS.2010.2080685

DO - 10.1109/TNS.2010.2080685

M3 - Article

AN - SCOPUS:79951683120

VL - 58

SP - 82

EP - 86

JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

SN - 0018-9499

IS - 1 PART 1

M1 - 5634154

ER -