Abstract
The concentrations of total protein, albumin and retinol-binding protein, a major transport protein for vitamin A, are significantly decreased by protein-calorie malnutrition. Weight-loss diets, sometimes involving severe energy deficits over prolonged periods of time, are common in the United States. The effect, if any, of prolonged low calorie weight-loss diets with normal intakes of protein on albumin, total protein and retinol-binding protein concentrations (and potentially on vitamin A metabolism) had not been extensively studied. We measured total protein, albumin, apo + holo retinol-binding protein and holo-free- and holo-transthyretin-bound retinol-binding protein concentrations during the course of a nutritionally adequate weight-loss diet (50% calorie restriction). We found that this type of dieting did not affect total protein, albumin or apo + holo, holo-free or holo-transthretin-bound retinol-binding protein concentrations significantly. This suggests that protein intake is more critical than caloric intake for retinol-binding protein status.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 484-486 |
| Number of pages | 3 |
| Journal | The Journal of Nutritional Biochemistry |
| Volume | 1 |
| Issue number | 9 |
| DOIs | |
| State | Published - 1990 |
| Externally published | Yes |
Fingerprint
Keywords
- calorie restriction
- human
- retinol-binding protein
- serum
- transthyretin
ASJC Scopus subject areas
- Biochemistry
- Endocrinology, Diabetes and Metabolism
Cite this
Effect of low-calorie diets on plasma retinol-binding protein concentrations in overweight women. / Burri, Betty Jane; Neidlinger, Terry R.; Van Loan, Marta; Keim, Nancy L.
In: The Journal of Nutritional Biochemistry, Vol. 1, No. 9, 1990, p. 484-486.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of low-calorie diets on plasma retinol-binding protein concentrations in overweight women
AU - Burri, Betty Jane
AU - Neidlinger, Terry R.
AU - Van Loan, Marta
AU - Keim, Nancy L.
PY - 1990
Y1 - 1990
N2 - The concentrations of total protein, albumin and retinol-binding protein, a major transport protein for vitamin A, are significantly decreased by protein-calorie malnutrition. Weight-loss diets, sometimes involving severe energy deficits over prolonged periods of time, are common in the United States. The effect, if any, of prolonged low calorie weight-loss diets with normal intakes of protein on albumin, total protein and retinol-binding protein concentrations (and potentially on vitamin A metabolism) had not been extensively studied. We measured total protein, albumin, apo + holo retinol-binding protein and holo-free- and holo-transthyretin-bound retinol-binding protein concentrations during the course of a nutritionally adequate weight-loss diet (50% calorie restriction). We found that this type of dieting did not affect total protein, albumin or apo + holo, holo-free or holo-transthretin-bound retinol-binding protein concentrations significantly. This suggests that protein intake is more critical than caloric intake for retinol-binding protein status.
AB - The concentrations of total protein, albumin and retinol-binding protein, a major transport protein for vitamin A, are significantly decreased by protein-calorie malnutrition. Weight-loss diets, sometimes involving severe energy deficits over prolonged periods of time, are common in the United States. The effect, if any, of prolonged low calorie weight-loss diets with normal intakes of protein on albumin, total protein and retinol-binding protein concentrations (and potentially on vitamin A metabolism) had not been extensively studied. We measured total protein, albumin, apo + holo retinol-binding protein and holo-free- and holo-transthyretin-bound retinol-binding protein concentrations during the course of a nutritionally adequate weight-loss diet (50% calorie restriction). We found that this type of dieting did not affect total protein, albumin or apo + holo, holo-free or holo-transthretin-bound retinol-binding protein concentrations significantly. This suggests that protein intake is more critical than caloric intake for retinol-binding protein status.
KW - calorie restriction
KW - human
KW - retinol-binding protein
KW - serum
KW - transthyretin
UR - http://www.scopus.com/inward/record.url?scp=0025001656&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025001656&partnerID=8YFLogxK
U2 - 10.1016/0955-2863(90)90085-Y
DO - 10.1016/0955-2863(90)90085-Y
M3 - Article
C2 - 15539240
AN - SCOPUS:0025001656
VL - 1
SP - 484
EP - 486
JO - Journal of Nutritional Biochemistry
JF - Journal of Nutritional Biochemistry
SN - 0955-2863
IS - 9
ER -