Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions

Y. S. Sun, J. P. Landry, Y. Y. Fei, J. T. Luo, X. B. Wang, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We study the kinetic effect of extrinsic fluorescent labeling agents on protein-ligand binding affinity and find that the kinetics is related to the loss or change of protein function when proteins are fluorescent-labeled.

Original languageEnglish (US)
Title of host publicationOptics InfoBase Conference Papers
PublisherOptical Society of America
ISBN (Print)9781557528599
StatePublished - 2008
EventConference on Lasers and Electro-Optics, CLEO 2008 - San Jose, CA, United States
Duration: May 4 2008May 9 2008

Other

OtherConference on Lasers and Electro-Optics, CLEO 2008
CountryUnited States
CitySan Jose, CA
Period5/4/085/9/08

Fingerprint

Labeling
marking
Ligands
proteins
Proteins
ligands
Kinetics
probes
kinetics
affinity

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Sun, Y. S., Landry, J. P., Fei, Y. Y., Luo, J. T., Wang, X. B., Lam, K., & Zhu, X. D. (2008). Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. In Optics InfoBase Conference Papers Optical Society of America.

Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. / Sun, Y. S.; Landry, J. P.; Fei, Y. Y.; Luo, J. T.; Wang, X. B.; Lam, Kit; Zhu, X. D.

Optics InfoBase Conference Papers. Optical Society of America, 2008.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sun, YS, Landry, JP, Fei, YY, Luo, JT, Wang, XB, Lam, K & Zhu, XD 2008, Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. in Optics InfoBase Conference Papers. Optical Society of America, Conference on Lasers and Electro-Optics, CLEO 2008, San Jose, CA, United States, 5/4/08.
Sun YS, Landry JP, Fei YY, Luo JT, Wang XB, Lam K et al. Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. In Optics InfoBase Conference Papers. Optical Society of America. 2008
Sun, Y. S. ; Landry, J. P. ; Fei, Y. Y. ; Luo, J. T. ; Wang, X. B. ; Lam, Kit ; Zhu, X. D. / Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. Optics InfoBase Conference Papers. Optical Society of America, 2008.
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