Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions

Y. S. Sun, J. P. Landry, Y. Y. Fei, J. T. Luo, X. B. Wang, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We study the kinetic effect of extrinsic fluorescent labeling agents on protein-ligand binding affinity and find that the kinetics is related to the loss or change of protein function when proteins are fluorescent-labeled.

Original languageEnglish (US)
Title of host publication2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS
DOIs
StatePublished - 2008
EventConference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS 2008 - San Jose, CA, United States
Duration: May 4 2008May 9 2008

Other

OtherConference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS 2008
CountryUnited States
CitySan Jose, CA
Period5/4/085/9/08

Fingerprint

Labeling
Ligands
Proteins
Kinetics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Sun, Y. S., Landry, J. P., Fei, Y. Y., Luo, J. T., Wang, X. B., Lam, K., & Zhu, X. D. (2008). Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. In 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS [4551561] https://doi.org/10.1109/CLEO.2008.4551561

Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. / Sun, Y. S.; Landry, J. P.; Fei, Y. Y.; Luo, J. T.; Wang, X. B.; Lam, Kit; Zhu, X. D.

2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS. 2008. 4551561.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sun, YS, Landry, JP, Fei, YY, Luo, JT, Wang, XB, Lam, K & Zhu, XD 2008, Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. in 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS., 4551561, Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS 2008, San Jose, CA, United States, 5/4/08. https://doi.org/10.1109/CLEO.2008.4551561
Sun YS, Landry JP, Fei YY, Luo JT, Wang XB, Lam K et al. Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. In 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS. 2008. 4551561 https://doi.org/10.1109/CLEO.2008.4551561
Sun, Y. S. ; Landry, J. P. ; Fei, Y. Y. ; Luo, J. T. ; Wang, X. B. ; Lam, Kit ; Zhu, X. D. / Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS. 2008.
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