Effect of estrogen on cerebral glucose metabolism in postmenopausal women

J. L. Eberling; Bruce R Reed; J. E. Coleman; W. J. Jagust

Effect of estrogen on cerebral glucose metabolism in postmenopausal women

J. L. Eberling, Bruce R Reed, J. E. Coleman, W. J. Jagust

Neurology

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

PET was used to evaluate the effect of estrogen use on regional cerebral glucose metabolism in postmenopausal women. Women receiving estrogen replacement therapy (ERT+), women not receiving estrogen (ERT-), and women with AD were studied. The ERT- group showed metabolic ratios that were intermediate to the ERT+ and AD groups, although they did not show any signs of cognitive impairment. These findings show an effect of estrogen depletion on brain metabolic activity.

Original language	English (US)
Pages (from-to)	875-877
Number of pages	3
Journal	Neurology
Volume	55
Issue number	6
State	Published - Sep 26 2000

ASJC Scopus subject areas

Neuroscience(all)

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title = "Effect of estrogen on cerebral glucose metabolism in postmenopausal women",

abstract = "PET was used to evaluate the effect of estrogen use on regional cerebral glucose metabolism in postmenopausal women. Women receiving estrogen replacement therapy (ERT+), women not receiving estrogen (ERT-), and women with AD were studied. The ERT- group showed metabolic ratios that were intermediate to the ERT+ and AD groups, although they did not show any signs of cognitive impairment. These findings show an effect of estrogen depletion on brain metabolic activity.",

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N2 - PET was used to evaluate the effect of estrogen use on regional cerebral glucose metabolism in postmenopausal women. Women receiving estrogen replacement therapy (ERT+), women not receiving estrogen (ERT-), and women with AD were studied. The ERT- group showed metabolic ratios that were intermediate to the ERT+ and AD groups, although they did not show any signs of cognitive impairment. These findings show an effect of estrogen depletion on brain metabolic activity.

AB - PET was used to evaluate the effect of estrogen use on regional cerebral glucose metabolism in postmenopausal women. Women receiving estrogen replacement therapy (ERT+), women not receiving estrogen (ERT-), and women with AD were studied. The ERT- group showed metabolic ratios that were intermediate to the ERT+ and AD groups, although they did not show any signs of cognitive impairment. These findings show an effect of estrogen depletion on brain metabolic activity.

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