Effect of dose on house finch infection with western equine encephalomyelitis and St. Louis encephalitis viruses

William Reisen, Robert Chiles, Vincent Martinez, Ying Fang, Emily Green, Sharon Clark

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

House finches, Carpodacus mexicanus, were experimentally infected with high and standard doses of western equine encephalomyelitis virus (WEEV) or St. Louis encephalitis virus (SLEV) to determine whether high doses would produce an elevated viremia response and a high frequency of chronic infections. Finches inoculated with ≈100,000 plaque forming units (PFU) of WEEV or SLEV produced viremia and antibody responses similar to those in finches inoculated with ≈100 PFU of WEEV or 1000 PFU of SLEV, the approximate quantities of virus expectorated by blood-feeding Culex tarsalis Coquillett. Infected finches were held through winter and then necropsied. Only one finch inoculated with the high dose of SLEV developed a chronic infection. Our data indicated that elevated infectious doses of virus may not increase the viremia level or the frequency of chronic infection in house finches.

Original languageEnglish (US)
Pages (from-to)978-981
Number of pages4
JournalJournal of Medical Entomology
Volume41
Issue number5
DOIs
StatePublished - Jan 1 2004

Fingerprint

Western Equine Encephalomyelitis
Western equine encephalomyelitis
St. Louis Encephalitis Viruses
Saint Louis encephalitis virus
Finches
Western equine encephalitis virus
viremia
Western Equine Encephalitis Viruses
Viremia
dosage
Infection
infection
Culex tarsalis
viruses
Viruses
Culex
antibodies
Antibody Formation
Carpodacus mexicanus
winter

Keywords

  • Chronic infections
  • House finches
  • Overwintering
  • St. Louis encephalitis
  • Western equine encephalomyelitis

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)
  • Insect Science
  • Infectious Diseases

Cite this

Effect of dose on house finch infection with western equine encephalomyelitis and St. Louis encephalitis viruses. / Reisen, William; Chiles, Robert; Martinez, Vincent; Fang, Ying; Green, Emily; Clark, Sharon.

In: Journal of Medical Entomology, Vol. 41, No. 5, 01.01.2004, p. 978-981.

Research output: Contribution to journalArticle

Reisen, William ; Chiles, Robert ; Martinez, Vincent ; Fang, Ying ; Green, Emily ; Clark, Sharon. / Effect of dose on house finch infection with western equine encephalomyelitis and St. Louis encephalitis viruses. In: Journal of Medical Entomology. 2004 ; Vol. 41, No. 5. pp. 978-981.
@article{f00d323c08884122bb883d13d76c9805,
title = "Effect of dose on house finch infection with western equine encephalomyelitis and St. Louis encephalitis viruses",
abstract = "House finches, Carpodacus mexicanus, were experimentally infected with high and standard doses of western equine encephalomyelitis virus (WEEV) or St. Louis encephalitis virus (SLEV) to determine whether high doses would produce an elevated viremia response and a high frequency of chronic infections. Finches inoculated with ≈100,000 plaque forming units (PFU) of WEEV or SLEV produced viremia and antibody responses similar to those in finches inoculated with ≈100 PFU of WEEV or 1000 PFU of SLEV, the approximate quantities of virus expectorated by blood-feeding Culex tarsalis Coquillett. Infected finches were held through winter and then necropsied. Only one finch inoculated with the high dose of SLEV developed a chronic infection. Our data indicated that elevated infectious doses of virus may not increase the viremia level or the frequency of chronic infection in house finches.",
keywords = "Chronic infections, House finches, Overwintering, St. Louis encephalitis, Western equine encephalomyelitis",
author = "William Reisen and Robert Chiles and Vincent Martinez and Ying Fang and Emily Green and Sharon Clark",
year = "2004",
month = "1",
day = "1",
doi = "10.1603/0022-2585-41.5.978",
language = "English (US)",
volume = "41",
pages = "978--981",
journal = "Journal of Medical Entomology",
issn = "0022-2585",
publisher = "Entomological Society of America",
number = "5",

}

TY - JOUR

T1 - Effect of dose on house finch infection with western equine encephalomyelitis and St. Louis encephalitis viruses

AU - Reisen, William

AU - Chiles, Robert

AU - Martinez, Vincent

AU - Fang, Ying

AU - Green, Emily

AU - Clark, Sharon

PY - 2004/1/1

Y1 - 2004/1/1

N2 - House finches, Carpodacus mexicanus, were experimentally infected with high and standard doses of western equine encephalomyelitis virus (WEEV) or St. Louis encephalitis virus (SLEV) to determine whether high doses would produce an elevated viremia response and a high frequency of chronic infections. Finches inoculated with ≈100,000 plaque forming units (PFU) of WEEV or SLEV produced viremia and antibody responses similar to those in finches inoculated with ≈100 PFU of WEEV or 1000 PFU of SLEV, the approximate quantities of virus expectorated by blood-feeding Culex tarsalis Coquillett. Infected finches were held through winter and then necropsied. Only one finch inoculated with the high dose of SLEV developed a chronic infection. Our data indicated that elevated infectious doses of virus may not increase the viremia level or the frequency of chronic infection in house finches.

AB - House finches, Carpodacus mexicanus, were experimentally infected with high and standard doses of western equine encephalomyelitis virus (WEEV) or St. Louis encephalitis virus (SLEV) to determine whether high doses would produce an elevated viremia response and a high frequency of chronic infections. Finches inoculated with ≈100,000 plaque forming units (PFU) of WEEV or SLEV produced viremia and antibody responses similar to those in finches inoculated with ≈100 PFU of WEEV or 1000 PFU of SLEV, the approximate quantities of virus expectorated by blood-feeding Culex tarsalis Coquillett. Infected finches were held through winter and then necropsied. Only one finch inoculated with the high dose of SLEV developed a chronic infection. Our data indicated that elevated infectious doses of virus may not increase the viremia level or the frequency of chronic infection in house finches.

KW - Chronic infections

KW - House finches

KW - Overwintering

KW - St. Louis encephalitis

KW - Western equine encephalomyelitis

UR - http://www.scopus.com/inward/record.url?scp=6444237303&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=6444237303&partnerID=8YFLogxK

U2 - 10.1603/0022-2585-41.5.978

DO - 10.1603/0022-2585-41.5.978

M3 - Article

VL - 41

SP - 978

EP - 981

JO - Journal of Medical Entomology

JF - Journal of Medical Entomology

SN - 0022-2585

IS - 5

ER -