Effect of Donor Milk Supplementation on Breastfeeding Outcomes in Term Newborns: A Randomized Controlled Trial

Laura R. Kair, Valerie J. Flaherman, Tarah T. Colaizy

Research output: Contribution to journalArticle

3 Scopus citations


Background. Pasteurized donor human milk (DHM) use for healthy newborns is increasing; however, no studies have explored its effect on breastfeeding outcomes. Patients and Methods. We enrolled 60 healthy, term breastfeeding newborns with ≥4.5% weight loss in the first 36 hours in a randomized controlled trial. Thirty newborns were randomly assigned to early limited-volume DHM supplementation and 30 newborns to exclusive breastfeeding. Mothers were surveyed at 1 week and 1, 2, and 3 months regarding the mode of infant feeding. Comparing infants randomized to DHM supplementation with those exclusively breastfeeding, there was no significant difference in the proportion using formula at 1 week (21% vs 7%, P =.15), nor in the proportion of any breastfeeding (79% vs 90%, P =.30) or breastfeeding without formula at 3 months (62% vs 77%, P =.27). Conclusion For newborns with ≥4.5% weight loss in the first 36 hours, early limited-volume supplementation with DHM is unlikely to have a significant favorable impact on breastfeeding outcomes.

Original languageEnglish (US)
JournalClinical Pediatrics
StatePublished - Jan 1 2019
Externally publishedYes



  • breast milk
  • breastfeeding
  • donor human milk
  • donor milk
  • milk banking
  • neonate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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