Abstract
GABA at 5%, but not 3%, of a low protein diet depressed food intake and growth of kittens. Adaptation to high protein prevented these effects. When cats adapted to low or high protein were fed a meal containing GABA, plasma GABA concentration after 2 hr was 8-fold higher in the low than in the high protein group; clearance was almost complete within 6 hr. Concentrations of proline, branched-chain, other large neutral and basic (especially ornithine) amino acids increased more when cats were fed a high rather than a low protein meal; glycine decreased. At 6 hr, concentrations had consistently returned to initial levels only in the low protein group. Feeding the high protein diet ad lib increased tissue concentrations of threonine, proline and the branched-chain amino acids. Hepatic or renal GABA-aminotransferase activity was not altered in kittens fed the high protein diet. Kidney activity was 10-fold that of liver, which may contribute to the better tolerance of GABA by cats than by rats.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 301-308 |
| Number of pages | 8 |
| Journal | Physiology and Behavior |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1984 |
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Keywords
- Cats
- Dietary GABA
- Dietary protein
- Food intake
- GABA-aminotransferase
- Growth
- Tissue amino acids
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Behavioral Neuroscience
Cite this
Effect of dietary protein and GABA on food intake, growth and tissue amino acids in cats. / Tews, Jean K.; Rogers, Quinton; Morris, James; Harper, Alfred E.
In: Physiology and Behavior, Vol. 32, No. 2, 01.01.1984, p. 301-308.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of dietary protein and GABA on food intake, growth and tissue amino acids in cats
AU - Tews, Jean K.
AU - Rogers, Quinton
AU - Morris, James
AU - Harper, Alfred E.
PY - 1984/1/1
Y1 - 1984/1/1
N2 - GABA at 5%, but not 3%, of a low protein diet depressed food intake and growth of kittens. Adaptation to high protein prevented these effects. When cats adapted to low or high protein were fed a meal containing GABA, plasma GABA concentration after 2 hr was 8-fold higher in the low than in the high protein group; clearance was almost complete within 6 hr. Concentrations of proline, branched-chain, other large neutral and basic (especially ornithine) amino acids increased more when cats were fed a high rather than a low protein meal; glycine decreased. At 6 hr, concentrations had consistently returned to initial levels only in the low protein group. Feeding the high protein diet ad lib increased tissue concentrations of threonine, proline and the branched-chain amino acids. Hepatic or renal GABA-aminotransferase activity was not altered in kittens fed the high protein diet. Kidney activity was 10-fold that of liver, which may contribute to the better tolerance of GABA by cats than by rats.
AB - GABA at 5%, but not 3%, of a low protein diet depressed food intake and growth of kittens. Adaptation to high protein prevented these effects. When cats adapted to low or high protein were fed a meal containing GABA, plasma GABA concentration after 2 hr was 8-fold higher in the low than in the high protein group; clearance was almost complete within 6 hr. Concentrations of proline, branched-chain, other large neutral and basic (especially ornithine) amino acids increased more when cats were fed a high rather than a low protein meal; glycine decreased. At 6 hr, concentrations had consistently returned to initial levels only in the low protein group. Feeding the high protein diet ad lib increased tissue concentrations of threonine, proline and the branched-chain amino acids. Hepatic or renal GABA-aminotransferase activity was not altered in kittens fed the high protein diet. Kidney activity was 10-fold that of liver, which may contribute to the better tolerance of GABA by cats than by rats.
KW - Cats
KW - Dietary GABA
KW - Dietary protein
KW - Food intake
KW - GABA-aminotransferase
KW - Growth
KW - Tissue amino acids
UR - http://www.scopus.com/inward/record.url?scp=0021253897&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021253897&partnerID=8YFLogxK
U2 - 10.1016/0031-9384(84)90145-8
DO - 10.1016/0031-9384(84)90145-8
M3 - Article
C2 - 6718555
AN - SCOPUS:0021253897
VL - 32
SP - 301
EP - 308
JO - Physiology and Behavior
JF - Physiology and Behavior
SN - 0031-9384
IS - 2
ER -