Effect of congenitally acquired Neospora caninum infection on risk of abortion and subsequent abortions in dairy cattle

Mark Thurmond, Sharon K. Hietala

Research output: Contribution to journalArticle

161 Citations (Scopus)

Abstract

Objectives - To estimate the extent to which abortion risk in dairy cattle during subsequent pregnancies was associated with congenitally-acquired Neospora caninum infection and previous abortions. Animals - 468 Holstein cattle. Procedure - Newborn heifer calves were tested for evidence of congenital infection attributable to N caninum and examined repeatedly until the completion of their second lactation for serologic status and evidence of abortion. Results - Compared with noninfected cows, congenitally infected cows had a 7.4-fold higher risk of abortion during their initial pregnancy and a 1.7-fold higher risk of aborting the first pregnancy during their first lactation. During the first pregnancy of their second lactation, congenitally infected cows that had aborted previously had a 5.6-fold higher risk of abortion, compared with cows that had not previously aborted and that were seronegative. The fetal risk period for N caninum-associated death began sooner and extended later during the initial pregnancy, compared with subsequent pregnancies. Conclusion - Congenitally acquired N caninum infection can cause a substantial number of abortions during the initial pregnancy of heifers, with abortion risk attributable to N caninum decreasing in subsequent pregnancies, possibly because of selective culling. Subsequent abortions can be expected in congenitally infected cows that have aborted previously.

Original languageEnglish (US)
Pages (from-to)1381-1385
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume58
Issue number12
StatePublished - Dec 1 1997

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Neospora
abortion (animals)
Neospora caninum
dairy cattle
pregnancy
Pregnancy
Infection
infection
cows
Lactation
lactation
heifers
culling (animals)
Induced Abortion
neonates
Holstein
calves
death
cattle

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Effect of congenitally acquired Neospora caninum infection on risk of abortion and subsequent abortions in dairy cattle. / Thurmond, Mark; Hietala, Sharon K.

In: American Journal of Veterinary Research, Vol. 58, No. 12, 01.12.1997, p. 1381-1385.

Research output: Contribution to journalArticle

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AB - Objectives - To estimate the extent to which abortion risk in dairy cattle during subsequent pregnancies was associated with congenitally-acquired Neospora caninum infection and previous abortions. Animals - 468 Holstein cattle. Procedure - Newborn heifer calves were tested for evidence of congenital infection attributable to N caninum and examined repeatedly until the completion of their second lactation for serologic status and evidence of abortion. Results - Compared with noninfected cows, congenitally infected cows had a 7.4-fold higher risk of abortion during their initial pregnancy and a 1.7-fold higher risk of aborting the first pregnancy during their first lactation. During the first pregnancy of their second lactation, congenitally infected cows that had aborted previously had a 5.6-fold higher risk of abortion, compared with cows that had not previously aborted and that were seronegative. The fetal risk period for N caninum-associated death began sooner and extended later during the initial pregnancy, compared with subsequent pregnancies. Conclusion - Congenitally acquired N caninum infection can cause a substantial number of abortions during the initial pregnancy of heifers, with abortion risk attributable to N caninum decreasing in subsequent pregnancies, possibly because of selective culling. Subsequent abortions can be expected in congenitally infected cows that have aborted previously.

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