Effect of chlorophyll-a, fluorouracil, and pituitrin on experimental acute pancreatitis

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Abstract

Intraductal administration of enterokinase in rats produced hyperamylasemia and acute hemorrhagic pancreatitis. This experimental pancreatitis and hyperamylasemia could be prevented by the concomitant intraductal injection of fluorouracil, pituitrin, or chlorophyll-a. The clinical implication of the study is that these agents, if given intraductally, may be useful in the prevention of iatrogenic hyperamylasemia and acute pancreatitis that may occur after endoscopic retrograde pancreatocholangiography.

Original languageEnglish (US)
Pages (from-to)79-81
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume103
Issue number2
StatePublished - 1979
Externally publishedYes

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Hyperamylasemia
Posterior Pituitary Hormones
Fluorouracil
Pancreatitis
Enteropeptidase
Injections
chlorophyll a

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

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title = "Effect of chlorophyll-a, fluorouracil, and pituitrin on experimental acute pancreatitis",
abstract = "Intraductal administration of enterokinase in rats produced hyperamylasemia and acute hemorrhagic pancreatitis. This experimental pancreatitis and hyperamylasemia could be prevented by the concomitant intraductal injection of fluorouracil, pituitrin, or chlorophyll-a. The clinical implication of the study is that these agents, if given intraductally, may be useful in the prevention of iatrogenic hyperamylasemia and acute pancreatitis that may occur after endoscopic retrograde pancreatocholangiography.",
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AB - Intraductal administration of enterokinase in rats produced hyperamylasemia and acute hemorrhagic pancreatitis. This experimental pancreatitis and hyperamylasemia could be prevented by the concomitant intraductal injection of fluorouracil, pituitrin, or chlorophyll-a. The clinical implication of the study is that these agents, if given intraductally, may be useful in the prevention of iatrogenic hyperamylasemia and acute pancreatitis that may occur after endoscopic retrograde pancreatocholangiography.

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