Effect of a Pre-Treatment Educational Video in Improving Patient Satisfaction with 5-Fluorouracil Treatment for Actinic Keratoses: A Randomized Controlled Trial

Oma Agbai, Parastoo Davari, Jennifer Johnson, April Armstrong, Nasim Fazel

Research output: Contribution to journalArticle

2 Scopus citations


Introduction: Patient treatment satisfaction and adherence may be affected by the initial understanding of outcomes in the treatment of actinic keratoses with 5-fluorouracil 5% cream (5-FU). Pre-treatment educational videos may optimize this understanding. The objective of this study was to determine whether prospective patient viewing of an educational video delineating treatment effects and expectations improves patient satisfaction and treatment completion rates for the treatment of actinic keratoses with 5-FU. Methods: Forty-four participants were recruited to the UC Davis Dermatology outpatient clinic. Each participant was randomized to the video (group A) or control group (group B), and topical 5-FU cream treatment was conducted for 2 weeks in both groups. Results: A follow-up questionnaire was performed to assess patient satisfaction and adherence to the treatment regimen. The results of these questions were analyzed using the Mann-Whitney test. One item on the questionnaire asked the patient to rate their overall level of satisfaction on a score of 0–100. The results of this question were analyzed using the unpaired t test. The results of the statistical analysis show no significant difference between the patient group that viewed the video and the patient group that did not view the video. Conclusions: We speculate that this study may establish a foundation for subsequent studies that may affect the broader medical community and promote development of educational videos.

Original languageEnglish (US)
Pages (from-to)675-681
Number of pages7
JournalDermatology and Therapy
Issue number4
StatePublished - Dec 1 2016



  • 5-fluorouracil
  • Actinic keratosis
  • Dermatology education
  • Patient education
  • Treatment video

ASJC Scopus subject areas

  • Dermatology

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