EEG monitoring of focal lesions of the blood-brain barrier

M. P. Remler, W. H. Marcussen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


This paper presents a modified method for the EEG detection and monitoring of small focal blood-brain barrier (BBB) lesions. The method uses high dose IV penicillin (1.2 x 106 μ/kg) to produce a spike focus at BBB lesions, penicillin encephalopathy. The EEG is recorded and the epileptic spikes are counted by an automatic computer program. The computer counting produces an objective quantitative result. The method is verified empirically on traumatic and radiation BBB lesions.

Original languageEnglish (US)
Pages (from-to)51-58
Number of pages8
JournalActa Neurologica Scandinavica
Issue number1
StatePublished - 1982

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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