EEG diagnoses of neonatal seizures: Clinical correlations and outcome

Mark S. Scher, Michael J. Painter, Ira Bergman, Mamdouha A. Barmada, James A Brunberg

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Electroencephalographic seizures were evaluated in 112 neonates. The first portion of the study involved 80 neonates with clinically identified abnormal movements, 8 of whom (10%) had electroencephalographic evidence of seizures coincident with this activity. Patients with abnormal movements (90%) had no concurrent electrical seizures. In the second part of the study, 40 infants who had electrical seizures were investigated. Eight of these infants had been identified during the first part of the study. Two-thirds of the patients (25) were premature. Sixteen patients (40%) died; 90% had brain lesions documented by computed tomography and/or postmortem study. Cerebral infarction and intraventricular hemorrhage were the most common lesions. One-third of the survivors (8 of 24 patients) were normal at a mean age of 3 years, while two-thirds had significant neurologic and developmental abnormalities. Neonatal seizures often are subtle, not associated with observable clinical expression, and associated with adverse development. Electroencephalographic confirmation is important in the evaluation of neonatal seizures.

Original languageEnglish (US)
Pages (from-to)17-24
Number of pages8
JournalPediatric Neurology
Volume5
Issue number1
DOIs
StatePublished - 1989
Externally publishedYes

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Electroencephalography
Seizures
Dyskinesias
Newborn Infant
Nervous System Malformations
Cerebral Infarction
Survivors
Tomography
Hemorrhage
Brain

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

EEG diagnoses of neonatal seizures : Clinical correlations and outcome. / Scher, Mark S.; Painter, Michael J.; Bergman, Ira; Barmada, Mamdouha A.; Brunberg, James A.

In: Pediatric Neurology, Vol. 5, No. 1, 1989, p. 17-24.

Research output: Contribution to journalArticle

Scher, Mark S. ; Painter, Michael J. ; Bergman, Ira ; Barmada, Mamdouha A. ; Brunberg, James A. / EEG diagnoses of neonatal seizures : Clinical correlations and outcome. In: Pediatric Neurology. 1989 ; Vol. 5, No. 1. pp. 17-24.
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