Edrophonium

An aid in the diagnosis of acute organophosphate poisoning

Ricardo A Maselli, J. H. Jacobsen, J. P. Spire

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Unsuspected accidental cutaneous exposure to an organophosphate insecticide caused flaccid paralysis in a 10-year-old girl. Electromyogram demonstrated repetitive compound muscle action potentials in response to a single stimulus of nerve; decremental response, more prominent at higher rates of stimulation; worsening of decremental response after edrophonium injection; and normal nerve conduction velocities. Electromyogram with repetitive nerve stimulation and an edrophonium test may provide a simple and rapid method for diagnosis of acute organophosphate poisoning.

Original languageEnglish (US)
Pages (from-to)508-510
Number of pages3
JournalAnnals of Neurology
Volume19
Issue number5
StatePublished - 1986
Externally publishedYes

Fingerprint

Edrophonium
Organophosphate Poisoning
Electromyography
Organophosphates
Neural Conduction
Insecticides
Paralysis
Action Potentials
Muscles
Skin
Injections

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Edrophonium : An aid in the diagnosis of acute organophosphate poisoning. / Maselli, Ricardo A; Jacobsen, J. H.; Spire, J. P.

In: Annals of Neurology, Vol. 19, No. 5, 1986, p. 508-510.

Research output: Contribution to journalArticle

Maselli, Ricardo A ; Jacobsen, J. H. ; Spire, J. P. / Edrophonium : An aid in the diagnosis of acute organophosphate poisoning. In: Annals of Neurology. 1986 ; Vol. 19, No. 5. pp. 508-510.
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