Early regression in social communication in autism spectrum disorders: A CPEA study

Rhiannon Luyster, Jennifer Richler, Susan Risi, Wan Ling Hsu, Geraldine Dawson, Raphael Bernier, Michelle Dunn, Susan Hepburn, Susan L. Hyman, William M. McMahon, Julie Goudie-Nice, Nancy Minshew, Sally J Rogers, Marian Sigman, M. Anne Spence, Wendy A. Goldberg, Helen Tager-Flusberg, Fred R. Volkmar, Catherine Lord

Research output: Contribution to journalArticlepeer-review

127 Scopus citations


In a multisite study of 351 children with autism spectrum disorders, 21 children with developmental delays, and 31 children with typical development, this study used caregiver interviews (i.e., the Autism Diagnostic Interview-Revised) at the time of entry into other research projects and follow-up telephone interviews designed for this project to describe the children's early acquisition and loss of social-communication milestones. Children who had used words spontaneously and meaningfully and then stopped talking were described by their caregivers as showing more gestures, greater participation in social games, and better receptive language before the loss and fewer of these skills after the loss than other children with autism spectrum disorders. A significant minority of children with autism without word loss showed a very similar pattern of loss of social-communication skills, a pattern not observed in the children with developmental delays or typical development.

Original languageEnglish (US)
Pages (from-to)311-336
Number of pages26
JournalDevelopmental Neuropsychology
Issue number3
StatePublished - 2005

ASJC Scopus subject areas

  • Psychology(all)
  • Developmental Neuroscience
  • Developmental and Educational Psychology
  • Experimental and Cognitive Psychology


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