Early-Childhood Social Reticence Predicts Brain Function in Preadolescent Youths During Distinct Forms of Peer Evaluation

Johanna M. Jarcho, Megan M. Davis, Tomer Shechner, Kathryn A. Degnan, Heather A. Henderson, Joel Stoddard, Nathan A. Fox, Ellen Leibenluft, Daniel S. Pine, Eric E. Nelson

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Social reticence is expressed as shy, anxiously avoidant behavior in early childhood. With development, overt signs of social reticence may diminish but could still manifest themselves in neural responses to peers. We obtained measures of social reticence across 2 to 7 years of age. At age 11, preadolescents previously characterized as high (n = 30) or low (n = 23) in social reticence completed a novel functional-MRI-based peer-interaction task that quantifies neural responses to the anticipation and receipt of distinct forms of social evaluation. High (but not low) social reticence in early childhood predicted greater activity in dorsal anterior cingulate cortex and left and right insula, brain regions implicated in processing salience and distress, when participants anticipated unpredictable compared with predictable feedback. High social reticence was also associated with negative functional connectivity between insula and ventromedial prefrontal cortex, a region commonly implicated in affect regulation. Finally, among participants with high social reticence, negative evaluation was associated with increased amygdala activity, but only during feedback from unpredictable peers.

Original languageEnglish (US)
Pages (from-to)821-835
Number of pages15
JournalPsychological science : a journal of the American Psychological Society / APS
Volume27
Issue number6
DOIs
StatePublished - Jun 1 2016
Externally publishedYes

Keywords

  • adolescent development
  • brain
  • neuroimaging
  • social cognition
  • social interaction

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychology(all)

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    Jarcho, J. M., Davis, M. M., Shechner, T., Degnan, K. A., Henderson, H. A., Stoddard, J., Fox, N. A., Leibenluft, E., Pine, D. S., & Nelson, E. E. (2016). Early-Childhood Social Reticence Predicts Brain Function in Preadolescent Youths During Distinct Forms of Peer Evaluation. Psychological science : a journal of the American Psychological Society / APS, 27(6), 821-835. https://doi.org/10.1177/0956797616638319