Duplex RNA-binding proteins are key players in a number of fields, including neurobiology, virology, and development. In this minireview, five human enzymes are discussed that bind duplex RNA through double-stranded RNA-binding motifs, including RNA-editing adenosine deaminases. Also highlighted are opportunities for advancing our understanding of these fascinating enzymes by chemical biology.
- Protein kinases
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry
- Biochemistry, Genetics and Molecular Biology(all)