Duplex RNA-binding enzymes: Headliners from neurobiology, virology, and development

Peter A. Beal

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Duplex RNA-binding proteins are key players in a number of fields, including neurobiology, virology, and development. In this minireview, five human enzymes are discussed that bind duplex RNA through double-stranded RNA-binding motifs, including RNA-editing adenosine deaminases. Also highlighted are opportunities for advancing our understanding of these fascinating enzymes by chemical biology.

Original languageEnglish (US)
Pages (from-to)257-266
Number of pages10
JournalChemBioChem
Volume6
Issue number2
DOIs
StatePublished - Feb 2005
Externally publishedYes

Keywords

  • Deaminases
  • Protein kinases
  • Proteins
  • Ribonucleases
  • RNA

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Biochemistry, Genetics and Molecular Biology(all)

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