Dual-site sampling improved detection rates for MRSA colonization in patients with cutaneous abscesses

Larissa S May, C. McCann, G. Brooks, R. Rothman, L. Miller, J. Jordan

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Extranasal sites are common reservoirs of Staphylococcus aureus colonization and may be relevant for methicillin-resistant S. aureus (MRSA) screening and infection control strategies. The objective here was to determine whether inguinal specimens could also be screened using Xpert SA Nasal Complete assay for MRSA. Results were compared to broth enrichment culture. Among 162 consented adults seeking care in the emergency department for cutaneous abscesses, inguinal specimens were found positive for MRSA more often than nares specimens, 24% and 26% by PCR or culture, respectively, compared to 19% each by PCR or culture. Overall, 6% of adults colonized with MRSA would have been missed by nares screening alone. Compared to culture, Xpert SA Nasal Complete assay demonstrated sensitivity and specificity of 89% and 97%, respectively, for detecting nares and/or inguinal MRSA colonization. In conclusion, inguinal specimens were a more common reservoir for MRSA than nares specimens in this population of patients.

Original languageEnglish (US)
Pages (from-to)79-82
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume80
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

Keywords

  • Cutaneous abscess
  • Emergency department
  • Infection control
  • Molecular diagnostics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Medicine(all)

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