Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma

Anupam Mitra, Jesus I. Luna, Alina I. Marusina, Alexander Merleev, Smriti Kundu-Raychaudhuri, David Fiorentino, Siba P Raychaudhuri, Emanual Michael Maverakis

Research output: Contribution to journalArticle

19 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)2873-2876
Number of pages4
JournalJournal of Investigative Dermatology
Volume135
Issue number11
DOIs
StatePublished - Nov 1 2015

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Smad2 Protein
TOR Serine-Threonine Kinases
Molecular Targeted Therapy
Imidazoles
Diffuse Scleroderma
Triazines
Needle Biopsy
Sirolimus
Transforming Growth Factor beta
Cultured Cells
Fibrosis
Fibroblasts
Biomarkers
Immunohistochemistry
Phosphorylation
Sensitivity and Specificity
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Dermatology
  • Biochemistry
  • Cell Biology
  • Molecular Biology

Cite this

Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis : Implications for Scleroderma. / Mitra, Anupam; Luna, Jesus I.; Marusina, Alina I.; Merleev, Alexander; Kundu-Raychaudhuri, Smriti; Fiorentino, David; Raychaudhuri, Siba P; Maverakis, Emanual Michael.

In: Journal of Investigative Dermatology, Vol. 135, No. 11, 01.11.2015, p. 2873-2876.

Research output: Contribution to journalArticle

Mitra A, Luna JI, Marusina AI, Merleev A, Kundu-Raychaudhuri S, Fiorentino D et al. Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma. Journal of Investigative Dermatology. 2015 Nov 1;135(11):2873-2876. https://doi.org/10.1038/jid.2015.252
Mitra, Anupam ; Luna, Jesus I. ; Marusina, Alina I. ; Merleev, Alexander ; Kundu-Raychaudhuri, Smriti ; Fiorentino, David ; Raychaudhuri, Siba P ; Maverakis, Emanual Michael. / Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis : Implications for Scleroderma. In: Journal of Investigative Dermatology. 2015 ; Vol. 135, No. 11. pp. 2873-2876.
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