Abstract
Droperidol is an antipsychotic and antiemetic drug that has been used extensively by Emergency Physicians, Psychiatrists, and Anesthesiologists worldwide since 1967. It also has been used effectively for other diverse conditions, such as treatment of headache and vertigo. As of January 2001, Droperidol was no longer available in Europe after its founder, Janssen-Cilag Pharmaceuticals, discontinued its distribution. In December 2001, the United States Food and Drug Administration (FDA) placed a black box warning on the use of Droperidol in response to an association between Droperidol and fatal cardiac dysrhythmias, such as torsade de pointes, resulting from prolongation of the QT interval. In this review we closely examine the pharmacology, indications, use, and complications associated with Droperidol, and speculate on its future use in the Emergency Department.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 441-447 |
| Number of pages | 7 |
| Journal | Journal of Emergency Medicine |
| Volume | 24 |
| Issue number | 4 |
| DOIs | |
| State | Published - May 2003 |
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Keywords
- Antipsychotic
- Droperidol
- Emergency Department
- FDA warning
- Inapsine
ASJC Scopus subject areas
- Emergency Medicine
Cite this
Droperidol in the Emergency Department : Is it safe? / Richards, John R; Schneir, Aaron B.
In: Journal of Emergency Medicine, Vol. 24, No. 4, 05.2003, p. 441-447.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Droperidol in the Emergency Department
T2 - Is it safe?
AU - Richards, John R
AU - Schneir, Aaron B.
PY - 2003/5
Y1 - 2003/5
N2 - Droperidol is an antipsychotic and antiemetic drug that has been used extensively by Emergency Physicians, Psychiatrists, and Anesthesiologists worldwide since 1967. It also has been used effectively for other diverse conditions, such as treatment of headache and vertigo. As of January 2001, Droperidol was no longer available in Europe after its founder, Janssen-Cilag Pharmaceuticals, discontinued its distribution. In December 2001, the United States Food and Drug Administration (FDA) placed a black box warning on the use of Droperidol in response to an association between Droperidol and fatal cardiac dysrhythmias, such as torsade de pointes, resulting from prolongation of the QT interval. In this review we closely examine the pharmacology, indications, use, and complications associated with Droperidol, and speculate on its future use in the Emergency Department.
AB - Droperidol is an antipsychotic and antiemetic drug that has been used extensively by Emergency Physicians, Psychiatrists, and Anesthesiologists worldwide since 1967. It also has been used effectively for other diverse conditions, such as treatment of headache and vertigo. As of January 2001, Droperidol was no longer available in Europe after its founder, Janssen-Cilag Pharmaceuticals, discontinued its distribution. In December 2001, the United States Food and Drug Administration (FDA) placed a black box warning on the use of Droperidol in response to an association between Droperidol and fatal cardiac dysrhythmias, such as torsade de pointes, resulting from prolongation of the QT interval. In this review we closely examine the pharmacology, indications, use, and complications associated with Droperidol, and speculate on its future use in the Emergency Department.
KW - Antipsychotic
KW - Droperidol
KW - Emergency Department
KW - FDA warning
KW - Inapsine
UR - http://www.scopus.com/inward/record.url?scp=0038365265&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038365265&partnerID=8YFLogxK
U2 - 10.1016/S0736-4679(03)00044-1
DO - 10.1016/S0736-4679(03)00044-1
M3 - Article
C2 - 12745049
AN - SCOPUS:0038365265
VL - 24
SP - 441
EP - 447
JO - Journal of Emergency Medicine
JF - Journal of Emergency Medicine
SN - 0736-4679
IS - 4
ER -