Dosimetric and clinical review of helical tomotherapy

Yi Rong, James S. Welsh

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


As a modality for delivering rotational therapy, helical tomotherapy offers dosimetric advantages by combining a continuously rotating gantry with a binary multileaf collimator. Helical tomotherapy, embodied in the TomoTherapy® Hi-Art II® system, delivers intensity-modulated fan beams in a helical pattern using binary multileaf collimator leaves while the couch is translated through the gantry. Helical tomotherapy offers the possibility of treating a variety of cases - from simple to complex - with improved target conformality and sensitive structure sparing compared with 3D or conventional static field IMRT plans, thereby allowing biologically effective dose escalation. For precise irradiation and possible treatment adaptation, the fully integrated on-board image-guidance system provides online volumetric images of patient anatomy using 3.5-MV x-ray beams and the xenon computed tomography detector. Several review articles were published before the year 2007 but emphasized the technical aspects of helical tomotherapy. In this article, we review very recent papers and focus on the dosimetric and clinical aspects of helical tomotherapy.

Original languageEnglish (US)
Pages (from-to)309-320
Number of pages12
JournalExpert Review of Anticancer Therapy
Issue number2
StatePublished - Feb 1 2011
Externally publishedYes


  • acute and late toxicities
  • adaptive radiotherapy
  • conformal avoidance
  • helical tomotherapy
  • image-guided radiotherapy
  • IMRT

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)


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