Abstract
Hemodialysis has come a long way since its early days and is a life sustaining therapy for millions of people with end-stage kidney disease throughout the world. Although thrice weekly hemodialysis remains the most common form of renal replacement therapy, other therapies such as more frequent, prolonged dialysis modalities have seen a rise recently. In this review, we compare and contrast methods for measuring the dialysis dose, with a focus on small molecule clearance (Kt/Vurea) among various dialysis modalities. We also describe newer on-line methods to measure dialysis and limitations to current adequacy measurement. Distinguishing dialysis adequacy from adequate treatment of the patient is also emphasized.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 471-475 |
| Number of pages | 5 |
| Journal | Seminars in Dialysis |
| Volume | 29 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 1 2016 |
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ASJC Scopus subject areas
- Nephrology
Cite this
Dose Targeting Metrics in Conventional and Intensive Maintenance Dialysis. / Ananthakrishnan, Shubha; Depner, Thomas A.
In: Seminars in Dialysis, Vol. 29, No. 6, 01.11.2016, p. 471-475.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Dose Targeting Metrics in Conventional and Intensive Maintenance Dialysis
AU - Ananthakrishnan, Shubha
AU - Depner, Thomas A.
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Hemodialysis has come a long way since its early days and is a life sustaining therapy for millions of people with end-stage kidney disease throughout the world. Although thrice weekly hemodialysis remains the most common form of renal replacement therapy, other therapies such as more frequent, prolonged dialysis modalities have seen a rise recently. In this review, we compare and contrast methods for measuring the dialysis dose, with a focus on small molecule clearance (Kt/Vurea) among various dialysis modalities. We also describe newer on-line methods to measure dialysis and limitations to current adequacy measurement. Distinguishing dialysis adequacy from adequate treatment of the patient is also emphasized.
AB - Hemodialysis has come a long way since its early days and is a life sustaining therapy for millions of people with end-stage kidney disease throughout the world. Although thrice weekly hemodialysis remains the most common form of renal replacement therapy, other therapies such as more frequent, prolonged dialysis modalities have seen a rise recently. In this review, we compare and contrast methods for measuring the dialysis dose, with a focus on small molecule clearance (Kt/Vurea) among various dialysis modalities. We also describe newer on-line methods to measure dialysis and limitations to current adequacy measurement. Distinguishing dialysis adequacy from adequate treatment of the patient is also emphasized.
UR - http://www.scopus.com/inward/record.url?scp=84992391500&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84992391500&partnerID=8YFLogxK
U2 - 10.1111/sdi.12526
DO - 10.1111/sdi.12526
M3 - Review article
C2 - 27592623
AN - SCOPUS:84992391500
VL - 29
SP - 471
EP - 475
JO - Seminars in Dialysis
JF - Seminars in Dialysis
SN - 0894-0959
IS - 6
ER -