Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?

Bouke C. De Jong, Anthony Onipede, Alex S. Pym, Sebastien Gagneux, Roxanne S. Aga, Kathryn DeRiemer, Peter M. Small

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.

Original languageEnglish (US)
Pages (from-to)3530-3532
Number of pages3
JournalJournal of Clinical Microbiology
Volume43
Issue number7
DOIs
StatePublished - Jul 2005
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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  • Cite this

    De Jong, B. C., Onipede, A., Pym, A. S., Gagneux, S., Aga, R. S., DeRiemer, K., & Small, P. M. (2005). Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis? Journal of Clinical Microbiology, 43(7), 3530-3532. https://doi.org/10.1128/JCM.43.7.3530-3532.2005