Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?

Bouke C. De Jong; Anthony Onipede; Alex S. Pym; Sebastien Gagneux; Roxanne S. Aga; Kathryn DeRiemer; Peter M. Small

doi:10.1128/JCM.43.7.3530-3532.2005

Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?

Bouke C. De Jong, Anthony Onipede, Alex S. Pym, Sebastien Gagneux, Roxanne S. Aga, Kathryn DeRiemer, Peter M. Small

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.

Original language	English (US)
Pages (from-to)	3530-3532
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	43
Issue number	7
DOIs	https://doi.org/10.1128/JCM.43.7.3530-3532.2005
State	Published - Jul 2005
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Microbiology

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@article{fc6073b117eb46b18040e99f2e5bbee9,

title = "Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?",

abstract = "Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.",

author = "{De Jong}, {Bouke C.} and Anthony Onipede and Pym, {Alex S.} and Sebastien Gagneux and Aga, {Roxanne S.} and Kathryn DeRiemer and Small, {Peter M.}",

year = "2005",

month = jul,

doi = "10.1128/JCM.43.7.3530-3532.2005",

language = "English (US)",

volume = "43",

pages = "3530--3532",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",