Does γ-tocopherol play a role in the primary prevention of heart disease and cancer? A review

Marion Dietrich, Maret G. Traber, Paul F. Jacques, Carroll E Cross, Youqing Hu, Gladys Block

Research output: Contribution to journalArticle

92 Scopus citations


Vitamin E consists of a group of eight isomers, four tocopherols (α-, β-, γ-, δ-tocopherol) and four tocotrienols (α-, β-, γ-, δ-tocotrienol). While extensive literature has been published on the potential health benefits of α-tocopherol, little is known about γ-tocopherol, the major form of vitamin E in food in the U.S. γ-tocopherol has recently received more research attention based on findings from in vitro and animal studies indicating that it has potent anti-inflammatory and antioxidant properties. Based on these recent studies, it is important to investigate the possible health benefits of γ-tocopherol in humans. In this article, we review publications on dietary γ-tocopherol intake, plasma γ-tocopherol levels, cardiovascular disease and cancer risk in humans.

Original languageEnglish (US)
Pages (from-to)292-299
Number of pages8
JournalJournal of the American College of Nutrition
Issue number4
StatePublished - Aug 2006



  • γ-tocopherol
  • Anti-inflammatory effects
  • Cancer
  • Dietary vitamin E
  • Human cardiovascular disease
  • Plasma γ-tocopherol

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

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