Documented reversal of global ischemia immediately after removal of an acute subdural hematoma. Report of two cases

M. L. Schroder, Jan Paul Muizelaar, A. J. Kuta

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Abstract

The authors report two cases of severe head injury with acute subdural hematoma, in which cerebral blood flow (CBF) and cerebral blood volume (CBV) measurements were obtained prior to evacuation of the subdural hematoma and again immediately after removal. The first patient, a 21-year-old man with a motor response localizing to pain, had a global CBF of 18.2 ml/100 gm/min and a decreased global CBV of 3.7 ml/100 gm at 2.3 hours after injury. Immediately after removal of the subdural hematoma (8.1 hours after injury). CBF and CBV measurements revealed increases to 35.5 ml/100 gm/min and 5.8 ml/100 gm, respectively. The second patient, a 49-year-old woman with a normal flexor motor response to pain, had preoperative global values of 15.8 ml/100 gm/min for CBF and 2.0 ml/100 gm for CBV at 3 hours after injury. Postoperatively (9.3 hours after injury), the CBF and CBV values increased to 41.6 ml/100 gm/min and 4.0 ml/100 gm, respectively. The first patient, with only borderline ischemia and removal of the subdural hematoma within 3 hours, made a good recovery, while the second patient, with prolonged lower levels of CBF, remained in a persistent vegetative state. The low values of preoperative CBV argue for compression of the microcirculation as the cause of ischemia.

Original languageEnglish (US)
Pages (from-to)324-327
Number of pages4
JournalJournal of Neurosurgery
Volume80
Issue number2
StatePublished - 1994
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Hematoma, Subdural, Acute
Ischemia
Subdural Hematoma
Wounds and Injuries
Persistent Vegetative State
Pain
Microcirculation
Craniocerebral Trauma
Cerebral Blood Volume

Keywords

  • acute subdural hematoma
  • cerebral blood flow
  • cerebral blood volume
  • ischemia
  • reperfusion
  • xenon-enhanced computerized tomography

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Documented reversal of global ischemia immediately after removal of an acute subdural hematoma. Report of two cases. / Schroder, M. L.; Muizelaar, Jan Paul; Kuta, A. J.

In: Journal of Neurosurgery, Vol. 80, No. 2, 1994, p. 324-327.

Research output: Contribution to journalArticle

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