Diversion colitis: Systematic evaluation of 636 cases with meta-Analysis

Nirmal S Mann, Joseph Leung, Sital S. Nagra, Kamyar Shahedi

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Objectives: This study was performed to characterize the clinical, endoscopic and histologic features of diversion colitis by performing a qualitative meta-Analysis of 636 cases of diversion colitis. Methods: The diagnosis of diversion colitis was made on a twenty two year old man based on clinical, endoscopic, and histological features. A PubMed search using terms such as diversion colitis, disuse colitis and bypass colitis without time or language barrier was performed. Qualitative Meta-Analysis was done using the well-established methods of qualitative research e.g. diagramming, theme repetition without serious contradiction, theme saturation and investigator reflexivity. Results: This search produced 636 cases of diversion colitis. Gender Information was available in 90.4%; there were 59.3% men. The mean age was 45 (Range 16-86) years. The mean incidence of diversion colitis after diversion was 70% (range 50-90%). The clinical features were crampy abdominal pain, bloody and mucoid anal discharge, diarrhea and massive rectal distension. The endoscopic features were erythema, friability, aphthous ulcers and mucus polyps. Histological features included acute and chronic inflammation, lymphoid follicular hyperplasia, crypt abnormalities, and changes of ischemia. Conclusion: Qualitative meta-Analysis on 636 cases of diversion colitis characterized clinical, endoscopic, histological features and possible pathogenetic mechanism and approach to management.

Original languageEnglish (US)
Pages (from-to)500-503
Number of pages4
JournalInternational Medical Journal
Issue number6
StatePublished - Jan 1 2015


  • Colostomy
  • Diversion colitis
  • Qualitative meta-analysis

ASJC Scopus subject areas

  • Medicine(all)


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