Abstract
Between 1995 and 1999 several cattle of a group of 80 heifers died acutely on a pasture in the Swiss Alps. The animals were found dead between July 9th and 15th each year. Only 1 animal was examined on post-mortem, and no significant lesions were found. Aconitum vulpera, A napellus, and Delphinium elatum were identified in the pasture. The presence of diterpenoid alkaloid-containing plants in the pasture, the rapid death of the animals, and the lack of pathologic lesions suggested diterpenoid alkaloid toxicosis as a cause of death. A multiresidue alkaloid screen using gas chromatography with a mass spectrometric detector was employed on rumen, abomasal, small intestine, and cecal contents from the I heifer. Deltaline, deltamine, and lycoctonine were identified. Aconitine was found in all gastrointestinal samples using a sensitive and highly specific liquid chromatography/mass spectrometry methodology for aconitine analysis. The findings of diterpenoid alkaloids in the gastrointestinal contents confirmed exposure to Delphinium and Aconitum spp, possibly resulting in sudden death.
Original language | English (US) |
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Pages (from-to) | 8-10 |
Number of pages | 3 |
Journal | Veterinary and Human Toxicology |
Volume | 44 |
Issue number | 1 |
State | Published - 2002 |
ASJC Scopus subject areas
- veterinary(all)
- Toxicology
- Health, Toxicology and Mutagenesis