Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS.

C. Heise, P. Vogel, Chris J Miller, A. Lackner, Satya Dandekar

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Intestinal tissues from SIV-infected rhesus macaques with subclinical as well as with terminal SIV disease were evaluated for SIV infection. SIV-infected mononuclear cells were detected throughout the gastrointestinal tract in all animals. In early infection, SIV-infected cells were diffusely distributed in lymphoid tissue and lamina propria, whereas in late stages of the disease, the viral infection was more severe and widely disseminated. Lymphoid cells of the lamina propria and gut-associated lymphoid tissue were the primary targets of SIV.

Original languageEnglish (US)
Pages (from-to)187-193
Number of pages7
JournalJournal of Medical Primatology
Volume22
Issue number2-3
StatePublished - Feb 1993

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Lymphoid Tissue
Macaca mulatta
gastrointestinal system
Gastrointestinal Tract
Mucous Membrane
Acquired Immunodeficiency Syndrome
laminae (animals)
Virus Diseases
Infection
infection
cells
Lymphocytes
digestive system
tissues
animals

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS. / Heise, C.; Vogel, P.; Miller, Chris J; Lackner, A.; Dandekar, Satya.

In: Journal of Medical Primatology, Vol. 22, No. 2-3, 02.1993, p. 187-193.

Research output: Contribution to journalArticle

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