Abstract
Intestinal tissues from SIV-infected rhesus macaques with subclinical as well as with terminal SIV disease were evaluated for SIV infection. SIV-infected mononuclear cells were detected throughout the gastrointestinal tract in all animals. In early infection, SIV-infected cells were diffusely distributed in lymphoid tissue and lamina propria, whereas in late stages of the disease, the viral infection was more severe and widely disseminated. Lymphoid cells of the lamina propria and gut-associated lymphoid tissue were the primary targets of SIV.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 187-193 |
| Number of pages | 7 |
| Journal | Journal of Medical Primatology |
| Volume | 22 |
| Issue number | 2-3 |
| State | Published - Feb 1993 |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
Cite this
Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS. / Heise, C.; Vogel, P.; Miller, Chris J; Lackner, A.; Dandekar, Satya.
In: Journal of Medical Primatology, Vol. 22, No. 2-3, 02.1993, p. 187-193.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS.
AU - Heise, C.
AU - Vogel, P.
AU - Miller, Chris J
AU - Lackner, A.
AU - Dandekar, Satya
PY - 1993/2
Y1 - 1993/2
N2 - Intestinal tissues from SIV-infected rhesus macaques with subclinical as well as with terminal SIV disease were evaluated for SIV infection. SIV-infected mononuclear cells were detected throughout the gastrointestinal tract in all animals. In early infection, SIV-infected cells were diffusely distributed in lymphoid tissue and lamina propria, whereas in late stages of the disease, the viral infection was more severe and widely disseminated. Lymphoid cells of the lamina propria and gut-associated lymphoid tissue were the primary targets of SIV.
AB - Intestinal tissues from SIV-infected rhesus macaques with subclinical as well as with terminal SIV disease were evaluated for SIV infection. SIV-infected mononuclear cells were detected throughout the gastrointestinal tract in all animals. In early infection, SIV-infected cells were diffusely distributed in lymphoid tissue and lamina propria, whereas in late stages of the disease, the viral infection was more severe and widely disseminated. Lymphoid cells of the lamina propria and gut-associated lymphoid tissue were the primary targets of SIV.
UR - http://www.scopus.com/inward/record.url?scp=0027549618&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027549618&partnerID=8YFLogxK
M3 - Article
C2 - 8411109
AN - SCOPUS:0027549618
VL - 22
SP - 187
EP - 193
JO - Journal of Medical Primatology
JF - Journal of Medical Primatology
SN - 0047-2565
IS - 2-3
ER -