Dissolution of gallstones using cholecystostomy tube in the pig

John P McGahan, L. L. Lee, H. Tesluk, T. G. Nyland, B. Ruebner, B. Schmidt

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.

Original languageEnglish (US)
Pages (from-to)201-205
Number of pages5
JournalInvestigative Radiology
Volume22
Issue number3
DOIs
StatePublished - 1987

Fingerprint

Cholecystostomy
Gallstones
Swine
Water
Catheters
Cholesterol
Cholecystitis
Gallbladder
monooctanoin

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Dissolution of gallstones using cholecystostomy tube in the pig. / McGahan, John P; Lee, L. L.; Tesluk, H.; Nyland, T. G.; Ruebner, B.; Schmidt, B.

In: Investigative Radiology, Vol. 22, No. 3, 1987, p. 201-205.

Research output: Contribution to journalArticle

McGahan, JP, Lee, LL, Tesluk, H, Nyland, TG, Ruebner, B & Schmidt, B 1987, 'Dissolution of gallstones using cholecystostomy tube in the pig', Investigative Radiology, vol. 22, no. 3, pp. 201-205. https://doi.org/10.1097/00004424-198703000-00003
McGahan, John P ; Lee, L. L. ; Tesluk, H. ; Nyland, T. G. ; Ruebner, B. ; Schmidt, B. / Dissolution of gallstones using cholecystostomy tube in the pig. In: Investigative Radiology. 1987 ; Vol. 22, No. 3. pp. 201-205.
@article{f7bb4b8437dc4d12ae60684dbd867c8f,
title = "Dissolution of gallstones using cholecystostomy tube in the pig",
abstract = "Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.",
author = "McGahan, {John P} and Lee, {L. L.} and H. Tesluk and Nyland, {T. G.} and B. Ruebner and B. Schmidt",
year = "1987",
doi = "10.1097/00004424-198703000-00003",
language = "English (US)",
volume = "22",
pages = "201--205",
journal = "Investigative Radiology",
issn = "0020-9996",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Dissolution of gallstones using cholecystostomy tube in the pig

AU - McGahan, John P

AU - Lee, L. L.

AU - Tesluk, H.

AU - Nyland, T. G.

AU - Ruebner, B.

AU - Schmidt, B.

PY - 1987

Y1 - 1987

N2 - Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.

AB - Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.

UR - http://www.scopus.com/inward/record.url?scp=0023150101&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023150101&partnerID=8YFLogxK

U2 - 10.1097/00004424-198703000-00003

DO - 10.1097/00004424-198703000-00003

M3 - Article

VL - 22

SP - 201

EP - 205

JO - Investigative Radiology

JF - Investigative Radiology

SN - 0020-9996

IS - 3

ER -