Abstract
Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 201-205 |
| Number of pages | 5 |
| Journal | Investigative Radiology |
| Volume | 22 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1987 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
Dissolution of gallstones using cholecystostomy tube in the pig. / McGahan, John P; Lee, L. L.; Tesluk, H.; Nyland, T. G.; Ruebner, B.; Schmidt, B.
In: Investigative Radiology, Vol. 22, No. 3, 1987, p. 201-205.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dissolution of gallstones using cholecystostomy tube in the pig
AU - McGahan, John P
AU - Lee, L. L.
AU - Tesluk, H.
AU - Nyland, T. G.
AU - Ruebner, B.
AU - Schmidt, B.
PY - 1987
Y1 - 1987
N2 - Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.
AB - Cholecystostomy catheters and human cholesterol gallstones were implanted surgically in the gallbladders of eight pigs. Through the catheters, mono-octanoin or sterile water (H2O) was infused from two to seven days. The mono-octanoin dissolved pure cholesterol gallstones smaller than 200 g. There was no stone dissolution with infusion of sterile water and only one stone larger than 250 g was dissolved with mono-octanoin. Side effects included moderate-to-severe inflammation and ulceration of the gallbladder with mono-octanoin instillation, which precludes its widespread use with the present treatment regimen. Infusion of water caused little gallbaldder irritation.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023150101&partnerID=8YFLogxK
U2 - 10.1097/00004424-198703000-00003
DO - 10.1097/00004424-198703000-00003
M3 - Article
C2 - 3557894
AN - SCOPUS:0023150101
VL - 22
SP - 201
EP - 205
JO - Investigative Radiology
JF - Investigative Radiology
SN - 0020-9996
IS - 3
ER -