Abstract
Various gallstone solvents are compared to evaluate their efficacy. Cholesterol gallstones from 5 patients were weight matched and incubated in 5 different solutions at 37° C. These solutions consisted of methyl-tertiary butyl ether (MTBE), 90% mono-octanoin (MO), absolute alcohol, normal saline, and water. Absolute alcohol and MTBE were found to induce faster stone dissolution than the mono-octanoin derivative. Concentrations of alcohol below 80%, normal saline, and water were not effective in dissolving stones. Newer agents such as MTBE may prove valuable in dissolution of stones in the human gallbladder or bile ducts.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 169-171 |
| Number of pages | 3 |
| Journal | Gastrointestinal Radiology |
| Volume | 11 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1986 |
Keywords
- Biliary tract, calculi
- Gallstones, effect of solvents
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Gastroenterology
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Cite this
Lee, L. L., & McGahan, J. P. (1986). Dissolution of cholesterol gallstones: Comparison of solvents. Gastrointestinal Radiology, 11(1), 169-171. https://doi.org/10.1007/BF02035062