Disseminated mucosal papilloma/condyloma secondary to human papillomavirus

John W Bishop, Jane M. Emanuel, Kenneth L. Sims

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

This report details the histopathologic findings in a woman who acquired the human papillomavirus 6/11 in her late teens and developed papilloma/condyloma of the nasopharynx, oropharynx, anogenital region, urethra, and urinary bladder. General evaluations of immune function reveal no defect, and there was no evidence of HIV infection. The morphologic expression of HPV 6/11 infection appears to be completely dependent on the mucosal epithelium affected. The complete spectrum of benign and premalignant epithelial changes induced by the human papillomavirus family - papilloma, verrucae, condyloma acuminatum, epithelial hyperplasia, and dysplasia - were present in this patient with a single papillomavirus infection. We postulate that this patient has a specific immune deficiency that limits her ability to control local infection and spread of the papillomavirus.

Original languageEnglish (US)
Pages (from-to)1291-1295
Number of pages5
JournalAmerican Journal of Surgical Pathology
Volume22
Issue number10
DOIs
StatePublished - Oct 1998
Externally publishedYes

Keywords

  • Condyloma
  • Disseminated condyloma
  • HPV
  • HPV 6/11
  • Human papillomavirus
  • Mucosa
  • Nasopharynx
  • Oropharynx
  • Papilloma
  • Perineum
  • Urethra
  • Urinary bladder
  • Vagina
  • Vulva

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

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