Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

Shachar Malka, Torrie Crabbs, Elizabeth B. Mitchell, Ashley Zehnder, Michael S Kent, Linda J Lowenstine, Michelle Hawkins

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

Original languageEnglish (US)
Pages (from-to)226-233
Number of pages8
JournalJournal of Avian Medicine and Surgery
Issue number3
StatePublished - Sep 2008
Externally publishedYes


  • Avian
  • Bubo virginianus
  • CD-3
  • Computed tomography
  • Endoscopy
  • Great horned owl
  • Immunohistochemistry
  • Lymphoma
  • T cell

ASJC Scopus subject areas

  • Small Animals


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