Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

Shachar Malka; Torrie Crabbs; Elizabeth B. Mitchell; Ashley Zehnder; Michael S Kent; Linda J Lowenstine; Michelle Hawkins

doi:10.1647/2007-048.1

Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

Shachar Malka, Torrie Crabbs, Elizabeth B. Mitchell, Ashley Zehnder, Michael S Kent, Linda J Lowenstine, Michelle Hawkins

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

Original language	English (US)
Pages (from-to)	226-233
Number of pages	8
Journal	Journal of Avian Medicine and Surgery
Volume	22
Issue number	3
DOIs	https://doi.org/10.1647/2007-048.1
State	Published - Sep 2008
Externally published	Yes

Keywords

Avian
Bubo virginianus
CD-3
Computed tomography
Endoscopy
Great horned owl
Immunohistochemistry
Lymphoma
T cell

ASJC Scopus subject areas

Small Animals

Access to Document

10.1647/2007-048.1

Cite this

Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus). / Malka, Shachar; Crabbs, Torrie; Mitchell, Elizabeth B.; Zehnder, Ashley; Kent, Michael S ; Lowenstine, Linda J ; Hawkins, Michelle.

In: Journal of Avian Medicine and Surgery, Vol. 22, No. 3, 09.2008, p. 226-233.

Research output: Contribution to journal › Article › peer-review

@article{215db5de4b65452abb32f855182e2304,

title = "Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)",

abstract = "A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.",

keywords = "Avian, Bubo virginianus, CD-3, Computed tomography, Endoscopy, Great horned owl, Immunohistochemistry, Lymphoma, T cell",

author = "Shachar Malka and Torrie Crabbs and Mitchell, {Elizabeth B.} and Ashley Zehnder and Kent, {Michael S} and Lowenstine, {Linda J} and Michelle Hawkins",

year = "2008",

month = sep,

doi = "10.1647/2007-048.1",

language = "English (US)",

volume = "22",

pages = "226--233",

journal = "Journal of Avian Medicine and Surgery",

issn = "1082-6742",

publisher = "Association of Avian Veterinarians",

number = "3",

}

TY - JOUR

T1 - Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

AU - Malka, Shachar

AU - Crabbs, Torrie

AU - Mitchell, Elizabeth B.

AU - Zehnder, Ashley

AU - Kent, Michael S

AU - Lowenstine, Linda J

AU - Hawkins, Michelle

PY - 2008/9

Y1 - 2008/9

N2 - A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

AB - A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

KW - Avian

KW - Bubo virginianus

KW - CD-3

KW - Computed tomography

KW - Endoscopy

KW - Great horned owl

KW - Immunohistochemistry

KW - Lymphoma

KW - T cell

UR - http://www.scopus.com/inward/record.url?scp=55949093446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=55949093446&partnerID=8YFLogxK

U2 - 10.1647/2007-048.1

DO - 10.1647/2007-048.1

M3 - Article

C2 - 19014096

AN - SCOPUS:55949093446

VL - 22

SP - 226

EP - 233

JO - Journal of Avian Medicine and Surgery

JF - Journal of Avian Medicine and Surgery

SN - 1082-6742

IS - 3

ER -

Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this