Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

Shachar Malka, Torrie Crabbs, Elizabeth B. Mitchell, Ashley Zehnder, Michael S Kent, Linda J Lowenstine, Michelle Hawkins

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

Original languageEnglish (US)
Pages (from-to)226-233
Number of pages8
JournalJournal of Avian Medicine and Surgery
Volume22
Issue number3
DOIs
StatePublished - Sep 2008
Externally publishedYes

Fingerprint

Bubo virginianus
Strigiformes
T-Cell Lymphoma
lymphoma
T-lymphocytes
parathyroid glands
thyroid gland
Raptors
birds of prey
Chlorambucil
clinical examination
Oropharynx
neck
Parathyroid Glands
biopsy
Respiratory Sounds
spleen
Diagnostic Imaging
weight loss
image analysis

Keywords

  • Avian
  • Bubo virginianus
  • CD-3
  • Computed tomography
  • Endoscopy
  • Great horned owl
  • Immunohistochemistry
  • Lymphoma
  • T cell

ASJC Scopus subject areas

  • Small Animals

Cite this

Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus). / Malka, Shachar; Crabbs, Torrie; Mitchell, Elizabeth B.; Zehnder, Ashley; Kent, Michael S; Lowenstine, Linda J; Hawkins, Michelle.

In: Journal of Avian Medicine and Surgery, Vol. 22, No. 3, 09.2008, p. 226-233.

Research output: Contribution to journalArticle

@article{215db5de4b65452abb32f855182e2304,
title = "Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)",
abstract = "A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.",
keywords = "Avian, Bubo virginianus, CD-3, Computed tomography, Endoscopy, Great horned owl, Immunohistochemistry, Lymphoma, T cell",
author = "Shachar Malka and Torrie Crabbs and Mitchell, {Elizabeth B.} and Ashley Zehnder and Kent, {Michael S} and Lowenstine, {Linda J} and Michelle Hawkins",
year = "2008",
month = "9",
doi = "10.1647/2007-048.1",
language = "English (US)",
volume = "22",
pages = "226--233",
journal = "Journal of Avian Medicine and Surgery",
issn = "1082-6742",
publisher = "Association of Avian Veterinarians",
number = "3",

}

TY - JOUR

T1 - Disseminated lymphoma of presumptive T-cell origin in a great horned owl (Bubo virginianus)

AU - Malka, Shachar

AU - Crabbs, Torrie

AU - Mitchell, Elizabeth B.

AU - Zehnder, Ashley

AU - Kent, Michael S

AU - Lowenstine, Linda J

AU - Hawkins, Michelle

PY - 2008/9

Y1 - 2008/9

N2 - A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

AB - A geriatric male great horned owl (Bubo virginianus) that was a resident at a raptor center was presented for examination because of stridor and weight loss. Results of physical examination, diagnostic imaging, and biopsy were consistent with disseminated lymphoma involving the oropharynx, neck region (including thyroid and parathyroid glands), keel, spleen, and liver. Attempts to treat the owl with chlorambucil failed, and the owl was euthanatized 5 months later. Neoplastic cells from this owl were immunoreactive to CD-3 antibody, suggesting the lymphoma was of T-cell origin.

KW - Avian

KW - Bubo virginianus

KW - CD-3

KW - Computed tomography

KW - Endoscopy

KW - Great horned owl

KW - Immunohistochemistry

KW - Lymphoma

KW - T cell

UR - http://www.scopus.com/inward/record.url?scp=55949093446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=55949093446&partnerID=8YFLogxK

U2 - 10.1647/2007-048.1

DO - 10.1647/2007-048.1

M3 - Article

C2 - 19014096

AN - SCOPUS:55949093446

VL - 22

SP - 226

EP - 233

JO - Journal of Avian Medicine and Surgery

JF - Journal of Avian Medicine and Surgery

SN - 1082-6742

IS - 3

ER -