Disseminated infection with Balamuthia mandrillaris in a dog

O. Foreman, J. Sykes, L. Ball, N. Yang, H. De Cock

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer pairs. Trophozoite and cystic forms of the amoeba were evident within the kidneys and brain parenchyma. This is the first report on a B. mandrillaris infection in a dog.

Original languageEnglish (US)
Pages (from-to)506-510
Number of pages5
JournalVeterinary Pathology
Issue number5
StatePublished - Sep 2004


  • Balamuthia mandrillaris
  • Brain
  • Canine
  • Immunohistochemistry
  • Kidney
  • Polymerase chain reaction

ASJC Scopus subject areas

  • veterinary(all)


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