Disseminated infection with Balamuthia mandrillaris in a dog

O. Foreman, Jane E Sykes, L. Ball, N. Yang, H. De Cock

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer pairs. Trophozoite and cystic forms of the amoeba were evident within the kidneys and brain parenchyma. This is the first report on a B. mandrillaris infection in a dog.

Original languageEnglish (US)
Pages (from-to)506-510
Number of pages5
JournalVeterinary Pathology
Volume41
Issue number5
DOIs
StatePublished - Sep 2004

Fingerprint

Balamuthia mandrillaris
Dogs
Great Dane
Trophozoites
trophozoites
nephritis
Meningoencephalitis
Amoeba
meningoencephalitis
Nephritis
dogs
Infection
infection
necropsy
polymerase chain reaction
kidneys
Staining and Labeling
Kidney
brain
Polymerase Chain Reaction

Keywords

  • Balamuthia mandrillaris
  • Brain
  • Canine
  • Immunohistochemistry
  • Kidney
  • Polymerase chain reaction

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Disseminated infection with Balamuthia mandrillaris in a dog. / Foreman, O.; Sykes, Jane E; Ball, L.; Yang, N.; De Cock, H.

In: Veterinary Pathology, Vol. 41, No. 5, 09.2004, p. 506-510.

Research output: Contribution to journalArticle

Foreman, O. ; Sykes, Jane E ; Ball, L. ; Yang, N. ; De Cock, H. / Disseminated infection with Balamuthia mandrillaris in a dog. In: Veterinary Pathology. 2004 ; Vol. 41, No. 5. pp. 506-510.
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