Disseminated Geosmithia argillacea infection in a German Shepherd dog

David C. Grant, Deanna A. Sutton, Christina A. Sandberg, Ronald D. Tyler, Elizabeth H. Thompson, Anna M Romanelli, Brian L. Wickes

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

Original languageEnglish (US)
Pages (from-to)221-226
Number of pages6
JournalMedical Mycology
Volume47
Issue number2
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

caspofungin
Itraconazole
itraconazole
Mycoses
mycoses
amphotericin B
German Shepherd
Penicillium
Amphotericin B
Aspergillus
Dogs
dogs
Infection
infection
animals
testing
posaconazole
Voriconazole
In Vitro Techniques

Keywords

  • Geosmithia argillacea
  • German Shepherd dog

ASJC Scopus subject areas

  • veterinary(all)
  • Infectious Diseases

Cite this

Grant, D. C., Sutton, D. A., Sandberg, C. A., Tyler, R. D., Thompson, E. H., Romanelli, A. M., & Wickes, B. L. (2009). Disseminated Geosmithia argillacea infection in a German Shepherd dog. Medical Mycology, 47(2), 221-226. https://doi.org/10.1080/13693780802559023

Disseminated Geosmithia argillacea infection in a German Shepherd dog. / Grant, David C.; Sutton, Deanna A.; Sandberg, Christina A.; Tyler, Ronald D.; Thompson, Elizabeth H.; Romanelli, Anna M; Wickes, Brian L.

In: Medical Mycology, Vol. 47, No. 2, 2009, p. 221-226.

Research output: Contribution to journalArticle

Grant, DC, Sutton, DA, Sandberg, CA, Tyler, RD, Thompson, EH, Romanelli, AM & Wickes, BL 2009, 'Disseminated Geosmithia argillacea infection in a German Shepherd dog', Medical Mycology, vol. 47, no. 2, pp. 221-226. https://doi.org/10.1080/13693780802559023
Grant, David C. ; Sutton, Deanna A. ; Sandberg, Christina A. ; Tyler, Ronald D. ; Thompson, Elizabeth H. ; Romanelli, Anna M ; Wickes, Brian L. / Disseminated Geosmithia argillacea infection in a German Shepherd dog. In: Medical Mycology. 2009 ; Vol. 47, No. 2. pp. 221-226.
@article{7b3fb7e85ae6488baff8e07ef9c68b97,
title = "Disseminated Geosmithia argillacea infection in a German Shepherd dog",
abstract = "We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.",
keywords = "Geosmithia argillacea, German Shepherd dog",
author = "Grant, {David C.} and Sutton, {Deanna A.} and Sandberg, {Christina A.} and Tyler, {Ronald D.} and Thompson, {Elizabeth H.} and Romanelli, {Anna M} and Wickes, {Brian L.}",
year = "2009",
doi = "10.1080/13693780802559023",
language = "English (US)",
volume = "47",
pages = "221--226",
journal = "Medical Mycology",
issn = "1369-3786",
publisher = "Informa Healthcare",
number = "2",

}

TY - JOUR

T1 - Disseminated Geosmithia argillacea infection in a German Shepherd dog

AU - Grant, David C.

AU - Sutton, Deanna A.

AU - Sandberg, Christina A.

AU - Tyler, Ronald D.

AU - Thompson, Elizabeth H.

AU - Romanelli, Anna M

AU - Wickes, Brian L.

PY - 2009

Y1 - 2009

N2 - We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

AB - We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

KW - Geosmithia argillacea

KW - German Shepherd dog

UR - http://www.scopus.com/inward/record.url?scp=59249100469&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=59249100469&partnerID=8YFLogxK

U2 - 10.1080/13693780802559023

DO - 10.1080/13693780802559023

M3 - Article

C2 - 19169949

AN - SCOPUS:59249100469

VL - 47

SP - 221

EP - 226

JO - Medical Mycology

JF - Medical Mycology

SN - 1369-3786

IS - 2

ER -