Dissecting the Dynamics of Corticothalamic Feedback

Henry J. Alitto, William Martin Usrey

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The thalamus and neocortex are intimately interconnected via a reciprocal arrangement of feedforward and feedback projections. In this issue of Neuron, Crandall etal. (2015) provide key insight into the functional dynamics of feedback projections and reveal the cellular and circuit mechanisms that underlie a rate-dependent switch in the net influence, suppression versus excitation, that cortex can exert on thalamic relay cells. The thalamus and neocortex are intimately interconnected via a reciprocal arrangement of feedforward and feedback projections. In this issue of Neuron, Crandall etal. (2015) provide key insight into the functional dynamics of feedback projections and reveal the cellular and circuit mechanisms that underlie a rate-dependent switch in the net influence, suppression versus excitation, that cortex can exert on thalamic relay cells.

Original languageEnglish (US)
Pages (from-to)605-607
Number of pages3
JournalNeuron
Volume86
Issue number3
DOIs
StatePublished - May 6 2015

ASJC Scopus subject areas

  • Neuroscience(all)

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