Abstract
An injectable preparation of flunixin meglumine was administered orally and intravenously at a dose of 1.1 mg/kg to six healthy adult horses in a cross-over design. Flunixin meglumine was detected in plasma within 15 min of administration and peak plasma concentrations were observed 45-60 min after oral administration. Mean bioavailability of the oral drug was 71.9 ± 26.0%, with an absorption half-life of 0.76 h. The apparent elimination half-life after oral administration was 2.4 h. The injectable preparation of flunixin meglumine is suitable for oral administration to horses.
Original language | English (US) |
---|---|
Pages (from-to) | 183-186 |
Number of pages | 4 |
Journal | Journal of Veterinary Pharmacology and Therapeutics |
Volume | 27 |
Issue number | 3 |
DOIs | |
State | Published - Jun 2004 |
Externally published | Yes |
ASJC Scopus subject areas
- Pharmacology
- veterinary(all)